214360-65-3

214360-65-3 - Names and Identifiers

Name	4,4,5,5-tetramethyl-2-[4-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane
Synonyms	4-Trifluoromethylphenylboronic Acid Pnacol Ester 4-Trifluoromethylphenylboronic acid pinacol ester 4-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER 4,4,5,5-TETRAMETHYL-2-(4-TRIFLUOROMETHYLPHENYL)-1,3,2-DIOXABOROLANE 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)trifluoromethylbenzene 4,4,5,5-Tetramethyl-2-[4-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane 2-(4-(trifluoroMethyl)phenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane 4,4,5,5-tetramethyl-2-[4-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[4-(trifluoromethyl)phenyl]- 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzene 4,4,5,5-tetramethyl-2-[4-(1,2,2-trifluoroethenoxy)phenyl]-1,3,2-dioxaborolane 4,4,5,5-Tetramethyl-2-[4-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane (This product is only available in Japan.)
CAS	214360-65-3
InChI	InChI=1/C14H16BF3O3/c1-13(2)14(3,4)21-15(20-13)9-5-7-10(8-6-9)19-12(18)11(16)17/h5-8H,1-4H3

214360-65-3 - Physico-chemical Properties

Molecular Formula	C13H16BF3O2
Molar Mass	272.07
Density	1.14±0.1 g/cm3(Predicted)
Melting Point	68-69 °C
Boling Point	291.4±40.0 °C(Predicted)
Flash Point	137.8°C
Vapor Presure	0.00159mmHg at 25°C
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.469

214360-65-3 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

214360-65-3 - Introduction

4,4,5,5-tetramethyl-2-[4-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane is an organic compound with the chemical formula C14H16BFO2. It has the following properties:

1. Appearance: colorless liquid.
2. Melting point:-45 ° C.
3. Boiling Point: 144 ° C.
4. Density: 1.12g/cm³.
5. Solubility: Soluble in some organic solvents, such as ethanol and dimethylformamide.

4,4,5,5-tetramethyl-2-[4-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane is mainly used as a reaction intermediate in organic synthesis. It can be used as a ligand or catalyst to participate in asymmetric catalytic reactions, oxidation reactions and substitution reactions. Specific application areas include organic synthesis, medicinal chemistry and materials science.

Preparation of 4,4,5,5-tetramethyl-2-[4-(trifluoromethyl)phenyl]-1,3, the method of 2-dioxaborolane can be obtained by reacting diethyl phenylborate with 4-trifluoromethylbenzyl alcohol under basic conditions.

Regarding safety information, in the absence of specific toxicity data and experimental sensitivity data, use should be followed by regular laboratory practices. At the same time, appropriate protective measures should be taken, such as wearing laboratory gloves, goggles and laboratory coats. During use and storage, contact with skin and eyes should be avoided, and a well-ventilated environment should be maintained. In addition, when dealing with waste, it should be handled and disposed of in accordance with relevant regulations.

Last Update：2024-04-09 21:11:58