22225-77-0
2-(difluoromethoxy)nitrobenzene
CAS: 22225-77-0
Molecular Formula: C7H5F2NO3
22225-77-0 - Names and Identifiers
| Name | 2-(difluoromethoxy)nitrobenzene |
| Synonyms | AKOS B016152 2-(difluoromethoxy)nitrobenzene 2-(DIFLUOROMETHOXY)NITROBENZENE 1-(DIFLUOROMETHOXY)-2-NITROBENZENE DIFLUOROMETHYL 2-NITROPHENYL ETHER 2-Nitro-1-(difluoromethoxy)benzene 1-(Difluoromethoxy)-2-nitrobenzene 1-(Difluoromethoxy)-2-nitrobenzene, alpha,alpha-Difluoro-2-nitroanisole |
| CAS | 22225-77-0 |
| InChI | InChI=1/C7H5F2NO3/c8-7(9)13-6-4-2-1-3-5(6)10(11)12/h1-4,7H |
22225-77-0 - Physico-chemical Properties
| Molecular Formula | C7H5F2NO3 |
| Molar Mass | 189.12 |
| Density | 1.384g/cm3 |
| Boling Point | 73 °C |
| Flash Point | 104.6°C |
| Vapor Presure | 0.0363mmHg at 25°C |
| Storage Condition | Room Temprature |
| Refractive Index | 1.494 |
22225-77-0 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S23 - Do not breathe vapour. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Class | IRRITANT |
22225-77-0 - Introduction
2-(difluoromethoxy) nitrbenzene is an organic compound with the chemical formula C7H5F2NO3. It is a colorless to light yellow solid with a peculiar odor. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow solid
-Melting Point: 45-48 ℃
-Boiling point: 165-167 ℃
-Density: 1.448g/cm³
-Solubility: Soluble in organic solvents such as alcohols, ethers and ketones, very slightly soluble in water
-Stability: relatively stable at room temperature, but sensitive to light and heat
Use:
-Chemical synthesis: 2-(difluoromethoxy) nitrbenzene can be used as an intermediate in certain organic syntheses. For example, it can be used in the synthesis of fluorine-containing organic compounds for pharmaceutical research and manufacturing.
-Chemical reaction: The compound can be reduced to difluoromethyl ether, or further functional group conversion through nucleophilic substitution reaction.
Method:
The preparation method of 2-(difluoromethoxy)nitrobenzene is more complicated. A common method is obtained by the reaction of nitric acid and 2-(difluoromethoxy) benzene alcohol. The specific operating conditions and procedures need to be carried out in a chemical laboratory.
Safety Information:
- 2-(difluoromethoxy)nitrobenzene is an organic compound that requires safe operation when used, such as wearing protective gloves, glasses and laboratory clothing.
-It may be toxic to the human body and may be irritating to the respiratory tract, skin and eyes. Avoid direct contact and inhalation of dust or gas.
-During storage and handling, avoid contact with oxidants, strong acids, and strong bases to prevent dangerous chemical reactions.
-Store it in a dry, ventilated place, away from fire and high temperature.
-In the event of a leak or accident, take appropriate emergency measures immediately and follow relevant handling and disposal procedures.
Please note that this compound is only used in a suitable laboratory environment. In practice, follow all safety and chemical laboratory procedures.
Nature:
-Appearance: Colorless to light yellow solid
-Melting Point: 45-48 ℃
-Boiling point: 165-167 ℃
-Density: 1.448g/cm³
-Solubility: Soluble in organic solvents such as alcohols, ethers and ketones, very slightly soluble in water
-Stability: relatively stable at room temperature, but sensitive to light and heat
Use:
-Chemical synthesis: 2-(difluoromethoxy) nitrbenzene can be used as an intermediate in certain organic syntheses. For example, it can be used in the synthesis of fluorine-containing organic compounds for pharmaceutical research and manufacturing.
-Chemical reaction: The compound can be reduced to difluoromethyl ether, or further functional group conversion through nucleophilic substitution reaction.
Method:
The preparation method of 2-(difluoromethoxy)nitrobenzene is more complicated. A common method is obtained by the reaction of nitric acid and 2-(difluoromethoxy) benzene alcohol. The specific operating conditions and procedures need to be carried out in a chemical laboratory.
Safety Information:
- 2-(difluoromethoxy)nitrobenzene is an organic compound that requires safe operation when used, such as wearing protective gloves, glasses and laboratory clothing.
-It may be toxic to the human body and may be irritating to the respiratory tract, skin and eyes. Avoid direct contact and inhalation of dust or gas.
-During storage and handling, avoid contact with oxidants, strong acids, and strong bases to prevent dangerous chemical reactions.
-Store it in a dry, ventilated place, away from fire and high temperature.
-In the event of a leak or accident, take appropriate emergency measures immediately and follow relevant handling and disposal procedures.
Please note that this compound is only used in a suitable laboratory environment. In practice, follow all safety and chemical laboratory procedures.
Last Update：2024-04-09 19:05:48
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