22227-25-4
3-(Trifluoromethyl)benzoic acid hydrazide
CAS: 22227-25-4
Molecular Formula: C8H7F3N2O
22227-25-4 - Names and Identifiers
| Name | 3-(Trifluoromethyl)benzoic acid hydrazide |
| Synonyms | BUTTPARK 30 1-47 3-(TRIFLUOROMETHYL)BENZHYDRAZIDE 3-(trifluoromethyl)benzohydrazide 3-(TRIFLUOROMETHYL)BENZOHYDRAZIDE 3-(TRIFLUOROMETHYL)BENZOIC ACID HYDRAZIDE 3-(Trifluoromethyl)benzoic acid hydrazide 3-(TRIFLUOROMETHYL)BENZENE-1-CARBOHYDRAZIDE 3-(Trifluoromethyl)benzene-1-carbohydrazide |
| CAS | 22227-25-4 |
| InChI | InChI=1/C8H7F3N2O/c9-8(10,11)6-3-1-2-5(4-6)7(14)13-12/h1-4H,12H2,(H,13,14) |
22227-25-4 - Physico-chemical Properties
| Molecular Formula | C8H7F3N2O |
| Molar Mass | 204.15 |
| Density | 1.356±0.06 g/cm3(Predicted) |
| Melting Point | 111 °C |
| pKa | 11.93±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.493 |
22227-25-4 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Note | Irritant |
22227-25-4 - Introduction
3-(Trifluoromethyl)benzoic acid hydrazide is an organic compound with the chemical formula C8H5F3N2O, with a benzoyl hydrazide group and a Trifluoromethyl group in the structure.
The following are some of the properties and uses of this compound:
-Appearance: White to beige crystalline solid.
-Melting point: About 172-175 degrees Celsius.
-Solubility: Soluble in common organic solvents, such as ethanol, ethyl acetate and dichloromethane.
-purpose: 3-(Trifluoromethyl)benzoic acid hydrazide can be used as raw materials and intermediates in organic synthesis. It can be used in the synthesis of fluorine-containing aromatic compounds, such as fluorine-containing oxalic acid derivatives, as well as the synthesis of other drugs, pesticides and materials.
Preparation Method:
3-(Trifluoromethyl)benzoic acid hydrazide can be prepared by reacting 3-trifluoromethylbenzoic acid with hydrazine. The reaction is carried out at normal temperature and under acidic conditions.
Safety Information:
3-(Trifluoromethyl)benzoic acid hydrazide has limited toxicity and hazard data, so the following should be noted when handling and using:
-Avoid inhaling dust or contact with skin, eyes and mouth.
-Wear appropriate protective equipment such as chemical goggles, gloves and protective clothing during operation.
-Operate under reasonable ventilation conditions.
-If necessary, operate in a chemical exhaust cabinet.
-Waste should be disposed of in accordance with local regulations and in accordance with relevant safe practices.
The following are some of the properties and uses of this compound:
-Appearance: White to beige crystalline solid.
-Melting point: About 172-175 degrees Celsius.
-Solubility: Soluble in common organic solvents, such as ethanol, ethyl acetate and dichloromethane.
-purpose: 3-(Trifluoromethyl)benzoic acid hydrazide can be used as raw materials and intermediates in organic synthesis. It can be used in the synthesis of fluorine-containing aromatic compounds, such as fluorine-containing oxalic acid derivatives, as well as the synthesis of other drugs, pesticides and materials.
Preparation Method:
3-(Trifluoromethyl)benzoic acid hydrazide can be prepared by reacting 3-trifluoromethylbenzoic acid with hydrazine. The reaction is carried out at normal temperature and under acidic conditions.
Safety Information:
3-(Trifluoromethyl)benzoic acid hydrazide has limited toxicity and hazard data, so the following should be noted when handling and using:
-Avoid inhaling dust or contact with skin, eyes and mouth.
-Wear appropriate protective equipment such as chemical goggles, gloves and protective clothing during operation.
-Operate under reasonable ventilation conditions.
-If necessary, operate in a chemical exhaust cabinet.
-Waste should be disposed of in accordance with local regulations and in accordance with relevant safe practices.
Last Update：2024-04-09 20:49:11
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