2376764-47-3

2376764-47-3 - Names and Identifiers

Name	tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate
Synonyms	tert-butyl (3E)-3-[(tetramethyl-1,3,2-dioxaborolan-2-yl)methylidene]piperidine-1-carboxylate tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate
CAS	2376764-47-3

2376764-47-3 - Physico-chemical Properties

Molecular Formula	C17H30BNO4
Molar Mass	323.24

2376764-47-3 - Introduction

tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl) piperidine-1-carboxylate, also known as tert-butyl ester 3-((4,4,5, 5-Tetramethyl -1,3, 2-dioxabororan-2-yl) methylene)piperidine-1-carboxylate (tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate), is an organic compound.

Nature:
-Appearance: solid powder or crystalline substance.
-Solubility: Soluble in common organic solvents.
-Melting point: About 70-75 ℃.

Use:
- tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate are often used as intermediates in organic synthesis to construct complex organic molecular structures.
-In the field of medicine, it can be used to synthesize anti-tumor drugs, antiviral drugs and other drugs.

Method:
tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl) piperidine-1-carboxylate can be prepared by various methods, A common method is through a nucleophilic substitution reaction: first, 4,4,5,5-tetramethyl-1,3, the 2-dioxabororane and 3-amino-1-piperidinecarboxylate are reacted to give the methylated product, which is subsequently reacted with the tert-butyl ester by acylation to give the final product.

Safety Information:
- tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate need to pay attention to fire prevention and explosion prevention during use and storage.
-Avoid contact with skin, eyes and respiratory tract and wear appropriate personal protective equipment when using.
-It should be used in a well-ventilated place, away from open flames or high temperatures.
-in the use and handling process, pay attention to comply with the relevant safety procedures.

Last Update：2024-04-09 21:01:54