25365-71-3
2-Phenylindole-3-carboxaldehyde
CAS: 25365-71-3
Molecular Formula: C15H11NO
25365-71-3 - Names and Identifiers
| Name | 2-Phenylindole-3-carboxaldehyde |
| Synonyms | AURORA 23280 AKOS SVR00140 ART-CHEM-BB B023284 OTAVA-BB BB7214110035 3-FORMYL-2-PHENYL-INDOLE 2-PHENYLINDOLE-3-ALDEHYDE 2-PHENYLINDOLE-3-CARBOXALDEHYDE 2-Phenylindole-3-carboxaldehyde 2-phenyl-1H-indole-3-carbaldehyde 2-PHENYL-1H-INDOLE-3-CARBALDEHYDE 1h-indole-3-carboxaldehyde, 2-phenyl- |
| CAS | 25365-71-3 |
| InChI | InChI=1/C15H11NO/c17-10-13-12-8-4-5-9-14(12)16-15(13)11-6-2-1-3-7-11/h1-10,16H |
25365-71-3 - Physico-chemical Properties
| Molecular Formula | C15H11NO |
| Molar Mass | 221.25 |
| Density | 1.237±0.06 g/cm3(Predicted) |
| Melting Point | 249-253 °C (lit.) |
| Boling Point | 462.9±33.0 °C(Predicted) |
| Flash Point | 237.5°C |
| Vapor Presure | 9.47E-09mmHg at 25°C |
| pKa | 15.30±0.30(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Air Sensitive |
| Refractive Index | 1.709 |
| MDL | MFCD00435481 |
25365-71-3 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
25365-71-3 - Introduction
It is a compound commonly used in organic synthesis. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless to light yellow crystal
-molecular formula: C15H11NO
-Molecular weight: 221.25g/mol
-Melting Point: 82-84 ℃
-Boiling point: 390 ℃ (expected)
Use:
It has a variety of uses in chemical experiments, including:
-As an intermediate in Organic Synthesis: It can be used to synthesize compounds with indole structure, such as indole derivatives and malachite green.
-As a fluorescent dye: It can be used as a fluorescent probe in cell and molecular microscopy to detect DNA, RNA and proteins.
Method:
The preparation method can be carried out by the following steps:
1. Indole and benzonitrile are reacted by heating in a suitable reaction solvent. The reaction is usually carried out within 1 to 5 hours.
2. Add an appropriate oxidizing agent, such as cuprous chloride or hydrogen peroxide, and continue the reaction.
3. The crude product is obtained by filtration and purified by appropriate purification methods (such as crystallization, washing, distillation).
Safety Information:
-may cause irritation to the eyes, skin, and respiratory system, so wear appropriate personal protective equipment, such as glasses, gloves, and face mask.
-Avoid inhalation, ingestion or contact with skin. Operate in a well-ventilated area or wear respiratory protective equipment.
-Be careful when handling the compound and avoid direct contact. Handle and store according to laboratory procedures.
-should be stored in a cool, dry, airtight container, away from fire and oxidizing agents.
Nature:
-Appearance: Colorless to light yellow crystal
-molecular formula: C15H11NO
-Molecular weight: 221.25g/mol
-Melting Point: 82-84 ℃
-Boiling point: 390 ℃ (expected)
Use:
It has a variety of uses in chemical experiments, including:
-As an intermediate in Organic Synthesis: It can be used to synthesize compounds with indole structure, such as indole derivatives and malachite green.
-As a fluorescent dye: It can be used as a fluorescent probe in cell and molecular microscopy to detect DNA, RNA and proteins.
Method:
The preparation method can be carried out by the following steps:
1. Indole and benzonitrile are reacted by heating in a suitable reaction solvent. The reaction is usually carried out within 1 to 5 hours.
2. Add an appropriate oxidizing agent, such as cuprous chloride or hydrogen peroxide, and continue the reaction.
3. The crude product is obtained by filtration and purified by appropriate purification methods (such as crystallization, washing, distillation).
Safety Information:
-may cause irritation to the eyes, skin, and respiratory system, so wear appropriate personal protective equipment, such as glasses, gloves, and face mask.
-Avoid inhalation, ingestion or contact with skin. Operate in a well-ventilated area or wear respiratory protective equipment.
-Be careful when handling the compound and avoid direct contact. Handle and store according to laboratory procedures.
-should be stored in a cool, dry, airtight container, away from fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
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View History
25365-71-3
2-Methylindan-1-one
1951-25-3
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878672-00-5
220727-26-4
1325-86-6
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811440-23-0
2-Methylindan-1-one
1951-25-3
123359-42-2
2315-81-3
878672-00-5
220727-26-4
1325-86-6
722533-18-8
811440-23-0