25566-04-5
3-Phenyl-3-azetidinol
CAS: 25566-04-5
Molecular Formula: C9H11NO
25566-04-5 - Names and Identifiers
| Name | 3-Phenyl-3-azetidinol |
| Synonyms | 3-Phenylazetidin-3-ol 3-Phenyl-3-azetidinol 3-Azetidinol, 3-phenyl- 3-hydroxy-3-phenylazetidine |
| CAS | 25566-04-5 |
25566-04-5 - Physico-chemical Properties
| Molecular Formula | C9H11NO |
| Molar Mass | 149.19 |
| Density | 1.178 |
| Melting Point | 154-156℃ |
| Boling Point | 265℃ |
| Flash Point | 125℃ |
25566-04-5 - Introduction
3-Phenyl-3-azetidinol(3-Phenyl-3-azetidinol) is an organic compound with the chemical formula C12H15NO, and the structure contains a phenyl group and an azetidine ring.
Nature:
-Appearance: Colorless to light yellow crystalline or solid
-Melting point: About 50-54 ° C
-Boiling point: About 315 ° C
-Solubility: Soluble in alcohol, ether and chloroform, almost insoluble in water.
Use:
- 3-Phenyl-3-azetidinol is often used as chiral inducer and chiral catalyst in organic synthesis, and plays an important role in the synthesis of chiral compounds and drugs.
-It can also be used to catalyze Asymmetric C- hydroxylation reactions and asymmetric imidization reactions.
Method:
The preparation of 3-Phenyl-3-azetidinol is generally obtained by the reduction reaction of azetidine and benzaldehyde:
1. At 150-200 C, azetidine reacts with benzaldehyde to produce 3-Phenyl-3-azetidinol.
2. After cooling crystallization and purification treatment, the target product can be obtained.
Safety Information:
3-Phenyl-3-azetidinol is a chemical that requires the following safety precautions:
-Avoid inhalation or contact with skin and eyes. Appropriate personal protective equipment such as lab gloves, masks and goggles should be worn during operation.
-It should be operated in a well-ventilated area to avoid dust and vapor.
-Please store and handle the compound in a suitable way, avoiding fire and high temperature.
Nature:
-Appearance: Colorless to light yellow crystalline or solid
-Melting point: About 50-54 ° C
-Boiling point: About 315 ° C
-Solubility: Soluble in alcohol, ether and chloroform, almost insoluble in water.
Use:
- 3-Phenyl-3-azetidinol is often used as chiral inducer and chiral catalyst in organic synthesis, and plays an important role in the synthesis of chiral compounds and drugs.
-It can also be used to catalyze Asymmetric C- hydroxylation reactions and asymmetric imidization reactions.
Method:
The preparation of 3-Phenyl-3-azetidinol is generally obtained by the reduction reaction of azetidine and benzaldehyde:
1. At 150-200 C, azetidine reacts with benzaldehyde to produce 3-Phenyl-3-azetidinol.
2. After cooling crystallization and purification treatment, the target product can be obtained.
Safety Information:
3-Phenyl-3-azetidinol is a chemical that requires the following safety precautions:
-Avoid inhalation or contact with skin and eyes. Appropriate personal protective equipment such as lab gloves, masks and goggles should be worn during operation.
-It should be operated in a well-ventilated area to avoid dust and vapor.
-Please store and handle the compound in a suitable way, avoiding fire and high temperature.
Last Update：2024-04-09 19:05:48
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Product Name: 3-Phenylazetidin-3-ol Visit Supplier Webpage Request for quotationCAS: 25566-04-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 3-Phenylazetidin-3-ol Request for quotationCAS: 25566-04-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
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