256376-65-5

256376-65-5 - Names and Identifiers

Name	1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 1-[(2-fluorophenyl)methyl]-
Synonyms	Riociguat-21 Riociguat Impurity K 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 1-[(2-fluoropheny... 1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile 1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 1-[(2-fluorophenyl)methyl]-
CAS	256376-65-5

256376-65-5 - Physico-chemical Properties

Molecular Formula	C14H9FN4
Molar Mass	252.25
Density	1.31±0.1 g/cm3(Predicted)
Melting Point	80-82oC
Boling Point	454.2±40.0 °C(Predicted)
Solubility	DMSO (Slightly), Methanol (Slightly)
Appearance	Solid
Color	Yellow to Dark Yellow
pKa	0.72±0.30(Predicted)
Storage Condition	2-8°C
Use	This product is for scientific research only and shall not be used for other purposes.

256376-65-5 - Introduction

1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 1-[(2-fluorophenyl)methyl]-, chemical formula C16H10FN3.

Nature:
1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 1-[(2-fluorophenyl)methyl]-is an organic compound. It is a white crystalline solid with a unique molecular structure. It has high thermal and chemical stability. The compound has good solubility in organic solvents.

Use:
1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 1-[(2-fluorophenyl)methyl]-has certain application value in the field of medicine. It can be used as a pharmaceutical intermediate for the synthesis of various biologically active compounds. In addition, it can also be used as a catalyst, ligand or reagent in organic synthesis reactions.

Method:
The preparation methods of 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile and 1-[(2-fluorophenyl)methyl]-are diversified. A common synthetic method is by reaction of pyrazolo [3,4-b] pyridine-3-methanone with 2-fluorobenzyl bromide to give the desired product. This reaction can be carried out at room temperature and the reaction conditions are relatively mild.

Safety Information:
1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 1-[(2-fluorophenyl)methyl]-needs to be handled properly. It belongs to organic compounds and has certain toxicity. Wear appropriate protective equipment such as gloves, goggles and laboratory clothing during use and operation. In addition, it should be stored in a dry, cool and well-ventilated place, away from fire and flammable materials. Avoid contact with substances such as oxidants and strong acids to avoid dangerous reactions. In the event of an accident, appropriate first aid measures should be taken immediately. The relevant safety data sheets and operating instructions should be consulted in detail before any experiments are carried out.

Last Update：2024-04-09 20:52:54