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256477-09-5

UK-371804

CAS: 256477-09-5

Molecular Formula: C14H16ClN5O4S

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256477-09-5 - Names and Identifiers

Name UK-371804
Synonyms UK-371804
Urokinase inhibitor 1
Urokinase inhitibor 1
UK-371804 (Urokinase inhitibor 1)
N-[[1-[(Aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methylalanine
Alanine, N-[[1-[(aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methyl-
CAS 256477-09-5

256477-09-5 - Physico-chemical Properties

Molecular FormulaC14H16ClN5O4S
Molar Mass385.83
Solubility DMSO: 10 mg/mL
Storage Condition-20℃
In vitro study UK-371804 is able to inhibit exogenous uPA in human chronic wound fluid (IC 50 =0.89 μM). UK-371804 has its excellent enzyme potency (K i =10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).
In vivo study In a porcine acute excisional wound model, following topical delivery, UK-371804 is able to penetrate into pig wounds and inhibit exogenous uPA activity with no adverse effect on wound healing parameters. Concentrations of UK-371804 in the dermis are 41.8 μM.

256477-09-5 - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.592 ml12.959 ml25.918 ml
5 mM0.518 ml2.592 ml5.184 ml
10 mM0.259 ml1.296 ml2.592 ml
5 mM0.052 ml0.259 ml0.518 ml
Last Update:2024-01-02 23:10:35
256477-09-5
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Shanghai Yuanye Bio-Technology Co., Ltd.
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Mobile: 18021002903
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Shanghai Amole Biotechnology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: UK-371804 Request for quotation
CAS: 256477-09-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: UK-371804  Visit Supplier Webpage Request for quotation
CAS: 256477-09-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: UK-371804 Visit Supplier Webpage Request for quotation
CAS: 256477-09-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: UK-371804 Visit Supplier Webpage Request for quotation
CAS: 256477-09-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: UK-371804 Visit Supplier Webpage Request for quotation
CAS: 256477-09-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
256477-09-5
巴柳氮二钠
4-Methyl-3-nitroanisole
DL-Aminovaleic Acid
162662-27-3
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