287394-20-1
(2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol
CAS: 287394-20-1
Molecular Formula: C9H10F3NO
287394-20-1 - Names and Identifiers
| Name | (2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol |
| Synonyms | (S)-2-AMino-2-(4-trifluoroMethylphenyl)ethanol (2S)-2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol (2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol (S)-2-amino-2-(4-(trifluoromethyl)phenyl)ethan-1-ol Benzeneethanol, β-amino-4-(trifluoromethyl)-, (βS)- (S)-2-amino-2-(4-(trifluoromethyl)phenyl)ethanol-HCl (2S)-2-AMINO-2-[4-(TRIFLUOROMETHYL)PHENYL]ETHAN-1-OL HCl |
| CAS | 287394-20-1 |
| InChI | InChI=1S/C9H10F3NO/c10-9(11,12)7-3-1-6(2-4-7)8(13)5-14/h1-4,8,14H,5,13H2/t8-/m1/s1 |
287394-20-1 - Physico-chemical Properties
| Molecular Formula | C9H10F3NO |
| Molar Mass | 205.18 |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
287394-20-1 - Introduction
(2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol, system name (2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Usually white solid
-Molecular formula: C10H11F3NO
-Molecular weight: 227.19g/mol
-Melting Point: 58-60 ℃
-Boiling point: 326 ℃
-Solubility: Slightly soluble in water, soluble in organic solvents such as alcohols and ethers
Use:
(2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol is a chiral compound commonly used as an intermediate for drug synthesis and resolution. Its Main uses include:
-Drug research: As an intermediate for the synthesis of drugs in the pharmaceutical field, it is used to synthesize biologically active compounds.
-non-dominant chirality: In the field of chiral analysis, it can be used as a chiral stationary phase for Chiral separation.
Method:
(2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol can be synthesized by the following reaction:
First, anisole is obtained through electrophilic substitution or nucleophilic substitution reaction; Then, anisole is converted into (2S) through reduction reaction -2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol.
Safety Information:
At present, there are few safety studies on (2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol, therefore, its specific toxicity and hazard information needs further research and verification. During use, care should be taken to follow the safety procedures of the chemical laboratory and wear appropriate protective equipment, such as gloves and goggles. In case of any discomfort or accident, seek medical help immediately.
Nature:
-Appearance: Usually white solid
-Molecular formula: C10H11F3NO
-Molecular weight: 227.19g/mol
-Melting Point: 58-60 ℃
-Boiling point: 326 ℃
-Solubility: Slightly soluble in water, soluble in organic solvents such as alcohols and ethers
Use:
(2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol is a chiral compound commonly used as an intermediate for drug synthesis and resolution. Its Main uses include:
-Drug research: As an intermediate for the synthesis of drugs in the pharmaceutical field, it is used to synthesize biologically active compounds.
-non-dominant chirality: In the field of chiral analysis, it can be used as a chiral stationary phase for Chiral separation.
Method:
(2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol can be synthesized by the following reaction:
First, anisole is obtained through electrophilic substitution or nucleophilic substitution reaction; Then, anisole is converted into (2S) through reduction reaction -2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol.
Safety Information:
At present, there are few safety studies on (2S)-2-Amino-2-[4-(trifluoromethyl)phenyl]ethanol, therefore, its specific toxicity and hazard information needs further research and verification. During use, care should be taken to follow the safety procedures of the chemical laboratory and wear appropriate protective equipment, such as gloves and goggles. In case of any discomfort or accident, seek medical help immediately.
Last Update：2024-04-09 21:01:54
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Product Name: (S)-2-AMino-2-(4-trifluoroMethylphenyl)ethanol Visit Supplier Webpage Request for quotationCAS: 287394-20-1
Tel: +86-400-900-4166
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CAS: 287394-20-1
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CAS: 287394-20-1
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