3-Bromo-4-hydroxypyridine
3-Bromo-4-hydroxypyridine
CAS: 36953-41-0
Molecular Formula: C5H4BrNO
3-Bromo-4-hydroxypyridine - Names and Identifiers
| Name | 3-Bromo-4-hydroxypyridine |
| Synonyms | 3-Bromopyridin-4-ol 3-Bromo-4-pyridinol 3-BROMO-4-PYRIDINOL 4-Pyridinol, 3-bromo- 3-bromopyridin-4(1H)-one 4-HYDROXY-3-BROMOPYRIDINE 3-Bromo-4-hydroxypyridine 3-BROMO-4-HYDROXYPYRIDINE Synthesis of 3-bromopyridin-4-ol |
| CAS | 36953-41-0 |
| InChI | InChI=1/C5H4BrNO/c6-4-3-7-2-1-5(4)8/h1-3H,(H,7,8) |
3-Bromo-4-hydroxypyridine - Physico-chemical Properties
| Molecular Formula | C5H4BrNO |
| Molar Mass | 174 |
| Density | 1.788±0.06 g/cm3(Predicted) |
| Melting Point | 225-230℃ |
| Boling Point | 338.2±22.0 °C(Predicted) |
| Flash Point | 101.6°C |
| Vapor Presure | 0.0306mmHg at 25°C |
| pKa | 3.71±0.18(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.6 |
| MDL | MFCD01646107 |
3-Bromo-4-hydroxypyridine - Introduction
3-Bromo-4-hydroxypyridine is an organic compound with a chemical formula of C5H4BrNO and a molecular weight of 156.99g/mol. It is a white to pale yellow solid with a peculiar bitter taste. The following is a description of some basic properties, uses, preparation and safety information about 3-Bromo-4-hydroxypyridine:
Nature:
1. Appearance: White to light yellow solid.
2. melting point: 101-104 ℃.
3. thermal stability: stable at room temperature, but may decompose at high temperature.
4. Solubility: Soluble in water, alcohols and some organic solvents, such as ethanol, dichloromethane and dimethylformamide.
Use:
1. As an intermediate in organic synthesis, it is widely used in the fields of medicine and pesticide.
2. in organic synthesis, the structural unit of 3-Bromo-4-hydroxypyridine can be introduced by intermolecular or intramolecular reactions, such as substitution reactions, addition reactions, etc.
3.3-Bromo-4-hydroxypyridine can also be used to synthesize other compounds, such as pyridine dyes and complexes, which have a wide range of applications in scientific research, industrial production and medical fields.
Preparation Method:
There are many preparation methods for 3-Bromo-4-hydroxypyridine. The common methods include the following steps:
1. An electrophilic substitution reaction is carried out using an alkali catalyst such as sodium hydroxide under the conditions of 3-bromopyridine to substitute a hydrogen atom with a hydroxyl group.
2. The product is extracted with an appropriate extraction agent (such as dichloromethane), and the pure product of 3-Bromo-4-hydroxypyridine is obtained by concentration and crystallization.
Safety Information:
1. 3-Bromo-4-hydroxypyridine is irritating to eyes and skin. Please avoid contact. If it comes into contact with skin or eyes, rinse with plenty of water immediately and seek medical assistance.
2. avoid inhalation or ingestion of the substance, such as inadvertent inhalation or ingestion, should promptly seek medical attention.
3. in operation, should use appropriate protective measures, such as wearing gloves, respiratory protection and safety glasses.
4. When stored, it should be sealed and kept away from fire and oxidant, and avoid contact with oxygen to avoid fire or explosion.
Please note that the above information provides a general description. In actual application, judgment and operation should be made according to the specific situation, and relevant regulations and safety operation procedures should be observed.
Nature:
1. Appearance: White to light yellow solid.
2. melting point: 101-104 ℃.
3. thermal stability: stable at room temperature, but may decompose at high temperature.
4. Solubility: Soluble in water, alcohols and some organic solvents, such as ethanol, dichloromethane and dimethylformamide.
Use:
1. As an intermediate in organic synthesis, it is widely used in the fields of medicine and pesticide.
2. in organic synthesis, the structural unit of 3-Bromo-4-hydroxypyridine can be introduced by intermolecular or intramolecular reactions, such as substitution reactions, addition reactions, etc.
3.3-Bromo-4-hydroxypyridine can also be used to synthesize other compounds, such as pyridine dyes and complexes, which have a wide range of applications in scientific research, industrial production and medical fields.
Preparation Method:
There are many preparation methods for 3-Bromo-4-hydroxypyridine. The common methods include the following steps:
1. An electrophilic substitution reaction is carried out using an alkali catalyst such as sodium hydroxide under the conditions of 3-bromopyridine to substitute a hydrogen atom with a hydroxyl group.
2. The product is extracted with an appropriate extraction agent (such as dichloromethane), and the pure product of 3-Bromo-4-hydroxypyridine is obtained by concentration and crystallization.
Safety Information:
1. 3-Bromo-4-hydroxypyridine is irritating to eyes and skin. Please avoid contact. If it comes into contact with skin or eyes, rinse with plenty of water immediately and seek medical assistance.
2. avoid inhalation or ingestion of the substance, such as inadvertent inhalation or ingestion, should promptly seek medical attention.
3. in operation, should use appropriate protective measures, such as wearing gloves, respiratory protection and safety glasses.
4. When stored, it should be sealed and kept away from fire and oxidant, and avoid contact with oxygen to avoid fire or explosion.
Please note that the above information provides a general description. In actual application, judgment and operation should be made according to the specific situation, and relevant regulations and safety operation procedures should be observed.
Last Update：2024-04-09 15:17:57
Supplier List
Featured ProductsSpot supply
Product Name: 3-Bromo-4-hydroxypyridine Visit Supplier Webpage Request for quotationCAS: 36953-41-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 3-Bromo-4-pyridinol Request for quotationCAS: 36953-41-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 3-Bromo-4-hydroxypyridine Visit Supplier Webpage Request for quotationCAS: 36953-41-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 3-BroMo-4-hydroxypyridine Visit Supplier Webpage Request for quotationCAS: 36953-41-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 3-Bromo-4-hydroxypyridine Visit Supplier Webpage Request for quotation
CAS: 36953-41-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 36953-41-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: 3-Bromo-4-hydroxypyridine Visit Supplier Webpage Request for quotationCAS: 36953-41-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 3-Bromo-4-pyridinol Request for quotationCAS: 36953-41-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 3-Bromo-4-hydroxypyridine Visit Supplier Webpage Request for quotationCAS: 36953-41-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 3-BroMo-4-hydroxypyridine Visit Supplier Webpage Request for quotationCAS: 36953-41-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 3-Bromo-4-hydroxypyridine Visit Supplier Webpage Request for quotation
CAS: 36953-41-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 36953-41-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History