3-Chloro-7-Nitro-1H-Indole
3-Chloro-7-Nitro-1H-Indole
CAS: 165669-14-7
Molecular Formula: C8H5ClN2O2
3-Chloro-7-Nitro-1H-Indole - Names and Identifiers
| Name | 3-Chloro-7-Nitro-1H-Indole |
| Synonyms | 3-Chloro-7-nitroindole 3-Chloro-7-Nitro-Indole 3-CHLORO-7-NITRO-INDOLE 3-CHLORO-7-NITRO-1H-INDOLE 3-Chloro-7-Nitro-1H-Indole 1H-Indole, 3-chloro-7-nitro- |
| CAS | 165669-14-7 |
| EINECS | 607-884-2 |
| InChI | InChI=1/C8H5ClN2O2/c9-6-4-10-8-5(6)2-1-3-7(8)11(12)13/h1-4,10H |
3-Chloro-7-Nitro-1H-Indole - Physico-chemical Properties
| Molecular Formula | C8H5ClN2O2 |
| Molar Mass | 196.59 |
| Density | 1.564±0.06 g/cm3(Predicted) |
| Boling Point | 395.7±22.0 °C(Predicted) |
| Flash Point | 193.1°C |
| Vapor Presure | 4.1E-06mmHg at 25°C |
| pKa | 12.38±0.30(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.726 |
3-Chloro-7-Nitro-1H-Indole - Introduction
It is an organic compound with the chemical formula C8H4ClNO2. The following is a description of its nature, use, preparation and safety information:
Nature:
is a yellow crystalline solid with a high melting and boiling point. It is hardly soluble in water at normal temperature, but soluble in organic solvents such as ethanol and acetone. It is a weakly alkaline compound that can form salt compounds.
Use:
It has strong biological activity and is often used as a raw material for pharmaceutical intermediates and fungicides. It can be used in the field of medicine for the synthesis of various drugs, such as anti-cancer drugs and antiviral drugs. In addition, it can be used as a reagent in organic synthesis, for example in the synthesis of natural products having an indole structure.
Method:
It can be prepared by reacting 3-chloro-7-nitrophenol with pyrrolidone under alkaline conditions. Specific preparation methods can be obtained by searching the chemical literature.
Safety Information:
During operation, care should be taken to prevent contact with skin, eyes and respiratory tract. Avoid contact with oxidizing agents during use and storage to avoid danger caused by the release of toxic gases. Due to its high melting and boiling points, care should be taken to use appropriate operating temperatures and ventilation facilities to avoid toxic fumes. Follow relevant safe operating procedures and wear appropriate personal protective equipment during handling.
Nature:
is a yellow crystalline solid with a high melting and boiling point. It is hardly soluble in water at normal temperature, but soluble in organic solvents such as ethanol and acetone. It is a weakly alkaline compound that can form salt compounds.
Use:
It has strong biological activity and is often used as a raw material for pharmaceutical intermediates and fungicides. It can be used in the field of medicine for the synthesis of various drugs, such as anti-cancer drugs and antiviral drugs. In addition, it can be used as a reagent in organic synthesis, for example in the synthesis of natural products having an indole structure.
Method:
It can be prepared by reacting 3-chloro-7-nitrophenol with pyrrolidone under alkaline conditions. Specific preparation methods can be obtained by searching the chemical literature.
Safety Information:
During operation, care should be taken to prevent contact with skin, eyes and respiratory tract. Avoid contact with oxidizing agents during use and storage to avoid danger caused by the release of toxic gases. Due to its high melting and boiling points, care should be taken to use appropriate operating temperatures and ventilation facilities to avoid toxic fumes. Follow relevant safe operating procedures and wear appropriate personal protective equipment during handling.
Last Update：2024-04-09 20:52:54
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View History
3-Chloro-7-Nitro-1H-Indole
2-METHYL-3-NITROBENZENEBORONIC ACID
氟铬酸吡啶酯(PFC)
Cyano-isoxazole
3-ME-2-BUTENYLIDENEBIS(TRICYCLOHEXYLPHOSPHINE)DICHLORORUTHE.
3'-溴-4-碘联苯
环丙基甲基肼双盐酸盐
2,6-二氯靛酚
2-methylthiazole-4-carbonitrile
3-ChlorobenzenecarboxiMidaMide hydrochloride
2-METHYL-3-NITROBENZENEBORONIC ACID
氟铬酸吡啶酯(PFC)
Cyano-isoxazole
3-ME-2-BUTENYLIDENEBIS(TRICYCLOHEXYLPHOSPHINE)DICHLORORUTHE.
3'-溴-4-碘联苯
环丙基甲基肼双盐酸盐
2,6-二氯靛酚
2-methylthiazole-4-carbonitrile
3-ChlorobenzenecarboxiMidaMide hydrochloride