3-Fluoro-2-methoxy-6-picoline
3-Fluoro-2-methoxy-6-picoline
CAS: 375368-80-2
Molecular Formula: C7H8FNO
3-Fluoro-2-methoxy-6-picoline - Names and Identifiers
| Name | 3-Fluoro-2-methoxy-6-picoline |
| Synonyms | 2-METHOXY-3-FLUORO-6-PICOLINE 3-FLUORO-2-METHOXY-6-PICOLINE 3-Fluoro-2-methoxy-6-picoline 2-methoxy-3,6-dimethylpyridine 3-Fluoro-2-methoxy-6-methylpyridine Pyridine, 3-fluoro-2-methoxy-6-methyl- Pyridine, 3-fluoro-2-methoxy-6-methyl- (9CI) |
| CAS | 375368-80-2 |
| InChI | InChI=1/C8H11NO/c1-6-4-5-7(2)9-8(6)10-3/h4-5H,1-3H3 |
3-Fluoro-2-methoxy-6-picoline - Physico-chemical Properties
| Molecular Formula | C7H8FNO |
| Molar Mass | 141.14 |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| Boling Point | 158.9±35.0 °C(Predicted) |
| Flash Point | 64.7°C |
| Vapor Presure | 1.11mmHg at 25°C |
| Appearance | Liquid |
| Color | Colorless to pale yellow |
| pKa | 1.70±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.496 |
3-Fluoro-2-methoxy-6-picoline - Introduction
It is an organic compound with the chemical formula C8H9FNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow liquid
-Molecular weight: 155.16g/mol
-Melting point: about -10 ℃
-Boiling point: 253-254 ℃
-Density: 1.175 g/mL
-Solubility: Soluble in common organic solvents, such as ether and alcohols
Use:
frequently used as intermediates and reagents for organic synthesis, with the following main uses:
-As an important intermediate in the synthesis of pesticides: It can be used to synthesize pesticides, herbicides and fungicides.
-used in the field of medicine: can be used for the synthesis of pharmaceutical active ingredients and pharmaceutical intermediates.
-It can be used to introduce fluorine, methoxy and other functional groups in organic synthesis.
Preparation Method:
The specific preparation method can vary according to different synthesis purposes, but it can usually be prepared by the following steps:
1. Pyridine compounds are generally obtained by selective fluoro substitution from pyridine to obtain 3-fluoro-2-methylpyridine.
2. React 3-fluoro-2-methylpyridine with methanol, introduce methoxy group through ester reaction, and generate phenanthrene exchange.
Safety Information:
When using and handling, you need to pay attention to the following safety matters:
-Irritating to skin, eyes and respiratory tract. Wear appropriate protective equipment such as gloves, goggles and masks.
-Avoid direct contact and avoid inhalation or ingestion.
-Use in a well-ventilated environment.
-Keep sealed during storage and store in a dry, cool place.
-When toxic substances are involved, they shall be handled and disposed in accordance with the corresponding regulations.
Please note that this information is for reference only. Please carefully read and follow the relevant safety instructions and operating procedures before using chemicals to ensure safe use.
Nature:
-Appearance: Colorless or light yellow liquid
-Molecular weight: 155.16g/mol
-Melting point: about -10 ℃
-Boiling point: 253-254 ℃
-Density: 1.175 g/mL
-Solubility: Soluble in common organic solvents, such as ether and alcohols
Use:
frequently used as intermediates and reagents for organic synthesis, with the following main uses:
-As an important intermediate in the synthesis of pesticides: It can be used to synthesize pesticides, herbicides and fungicides.
-used in the field of medicine: can be used for the synthesis of pharmaceutical active ingredients and pharmaceutical intermediates.
-It can be used to introduce fluorine, methoxy and other functional groups in organic synthesis.
Preparation Method:
The specific preparation method can vary according to different synthesis purposes, but it can usually be prepared by the following steps:
1. Pyridine compounds are generally obtained by selective fluoro substitution from pyridine to obtain 3-fluoro-2-methylpyridine.
2. React 3-fluoro-2-methylpyridine with methanol, introduce methoxy group through ester reaction, and generate phenanthrene exchange.
Safety Information:
When using and handling, you need to pay attention to the following safety matters:
-Irritating to skin, eyes and respiratory tract. Wear appropriate protective equipment such as gloves, goggles and masks.
-Avoid direct contact and avoid inhalation or ingestion.
-Use in a well-ventilated environment.
-Keep sealed during storage and store in a dry, cool place.
-When toxic substances are involved, they shall be handled and disposed in accordance with the corresponding regulations.
Please note that this information is for reference only. Please carefully read and follow the relevant safety instructions and operating procedures before using chemicals to ensure safe use.
Last Update：2024-04-09 19:05:50
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CAS: 375368-80-2
Tel: 18301782025
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View History
3-Fluoro-2-methoxy-6-picoline
103438-86-4
14985-44-5
12269-86-2
1120-06-5
1119-97-7
7224-66-0
环戊烷
1634-04-4
183062-92-2
103438-86-4
14985-44-5
12269-86-2
1120-06-5
1119-97-7
7224-66-0
环戊烷
1634-04-4
183062-92-2