3-Fluoro-5-hydroxypyridine
3-Fluoro-5-hydroxypyridine
CAS: 209328-55-2
Molecular Formula: C5H4FNO
3-Fluoro-5-hydroxypyridine - Names and Identifiers
| Name | 3-Fluoro-5-hydroxypyridine |
| Synonyms | 5-Fluoropyridin-3-ol 3-pyridinol, 5-fluoro- 3-Fluoro-5-hydroxypyridine 3-Pyridinol,5-fluoro-(9CI) 5-Fluoro-3-hydroxypyridine 3-Fluoro-5-hydroxypyrudune 3-FLUORO-5-HYDROXYPYRIDINE HCPY3003-Fluoro-5-hydroxypyridine |
| CAS | 209328-55-2 |
| InChI | InChI=1/C5H4FNO/c6-4-1-5(8)3-7-2-4/h1-3,8H |
3-Fluoro-5-hydroxypyridine - Physico-chemical Properties
| Molecular Formula | C5H4FNO |
| Molar Mass | 113.09 |
| Density | 1.325±0.06 g/cm3(Predicted) |
| Melting Point | 161-164℃ |
| Boling Point | 303.0±22.0 °C(Predicted) |
| Flash Point | 137°C |
| Vapor Presure | 0.000534mmHg at 25°C |
| Appearance | White powder |
| pKa | 8.38±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.526 |
3-Fluoro-5-hydroxypyridine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. |
| HS Code | 29339900 |
3-Fluoro-5-hydroxypyridine - Introduction
3-Fluoro-5-hydroxypyridine is an organic compound with the chemical formula C5H4FNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-Fluoro-5-hydroxypyridine is a colorless to light yellow crystal or powder.
-Solubility: Soluble in water, alcohol and ether solvents.
Use:
-As a chemical reagent: 3-Fluoro-5-hydroxypyridine is often used as a reagent in organic synthesis and acts as a catalyst in some chemical reactions.
-Pharmaceutical field: It is also used in the synthesis of certain drugs, such as the synthesis of certain anti-cancer drugs.
-Other uses: In addition to the above uses, 3-Fluoro-5-hydroxypyridine can also be used in the production of dyes, fragrances and other chemicals.
Method:
3-Fluoro-5-hydroxypyridine has many preparation methods, among which the common methods include the following:
-3-fluoropyridine is obtained by fluorination reaction of pyridine, and then 3-Fluoro-5-hydroxypyridine is obtained by oxidation reaction.
-Through The nitration reaction of pyridine, and then through the fluorination reaction and reduction reaction, 3-Fluoro-5-hydroxypyridine is finally obtained.
Safety Information:
-3-fluoro-5-hydroxyypyridine should be stored properly, avoid exposure to sunlight and high temperature environment.
-Appropriate personal protective measures, such as wearing protective glasses, gloves and laboratory coats, must be followed.
-When using and handling, you need to comply with the laboratory's safe operating regulations and handling guidelines for related chemicals.
Please note that when using and handling chemicals, follow appropriate safety practices, such as wearing personal protective equipment, ensuring that the operating area is well ventilated, and properly disposing of waste in accordance with relevant regulations.
Nature:
-Appearance: 3-Fluoro-5-hydroxypyridine is a colorless to light yellow crystal or powder.
-Solubility: Soluble in water, alcohol and ether solvents.
Use:
-As a chemical reagent: 3-Fluoro-5-hydroxypyridine is often used as a reagent in organic synthesis and acts as a catalyst in some chemical reactions.
-Pharmaceutical field: It is also used in the synthesis of certain drugs, such as the synthesis of certain anti-cancer drugs.
-Other uses: In addition to the above uses, 3-Fluoro-5-hydroxypyridine can also be used in the production of dyes, fragrances and other chemicals.
Method:
3-Fluoro-5-hydroxypyridine has many preparation methods, among which the common methods include the following:
-3-fluoropyridine is obtained by fluorination reaction of pyridine, and then 3-Fluoro-5-hydroxypyridine is obtained by oxidation reaction.
-Through The nitration reaction of pyridine, and then through the fluorination reaction and reduction reaction, 3-Fluoro-5-hydroxypyridine is finally obtained.
Safety Information:
-3-fluoro-5-hydroxyypyridine should be stored properly, avoid exposure to sunlight and high temperature environment.
-Appropriate personal protective measures, such as wearing protective glasses, gloves and laboratory coats, must be followed.
-When using and handling, you need to comply with the laboratory's safe operating regulations and handling guidelines for related chemicals.
Please note that when using and handling chemicals, follow appropriate safety practices, such as wearing personal protective equipment, ensuring that the operating area is well ventilated, and properly disposing of waste in accordance with relevant regulations.
Last Update：2024-04-09 15:17:55
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