30216-57-0
1,3-Thiazole-2-carbonyl chloride
CAS: 30216-57-0
Molecular Formula: C4H2ClNOS
30216-57-0 - Names and Identifiers
30216-57-0 - Physico-chemical Properties
| Molecular Formula | C4H2ClNOS |
| Molar Mass | 147.58 |
| Density | 1.497±0.06 g/cm3(Predicted) |
| Melting Point | 54-58 °C |
| Boling Point | 244.7±23.0 °C(Predicted) |
| Flash Point | 101.8°C |
| Vapor Presure | 0.0299mmHg at 25°C |
| pKa | -0.51±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.583 |
30216-57-0 - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R14 - Reacts violently with water R22 - Harmful if swallowed R29 - Contact with water liberates toxic gas R34 - Causes burns R36 - Irritating to the eyes |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S30 - Never add water to this product. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3261 8 / PGIII |
| WGK Germany | 3 |
| HS Code | 29349990 |
| Hazard Note | Corrosive |
30216-57-0 - Introduction
1,3-thiazole-2-carbonyl chloride is an organic compound with the chemical formula C4H3ClNOS. It is a colorless liquid with a pungent odor. It has low toxicity, but can cause irritation on contact with the skin and inhalation.
1,3-thiazole-2-carbonyl chloride is an important organic synthesis intermediate. It is commonly used in the synthesis of pharmaceuticals, pesticides, dyes and other organic compounds. It is often used in drug research to synthesize antibiotics, anticancer drugs, antiviral drugs, etc. In addition, it can also be used to synthesize biologically active molecules and functional materials.
The method for preparing 1,3-thiazole-2-carbonyl chloride is usually obtained by reacting 1,3-thiazole-2-formyloxime with thionyl chloride. This reaction is carried out at room temperature using thionyl chloride as a reaction solvent.
Pay attention to safety when using and storing 1,3-thiazole-2-carbonyl chloride. Appropriate personal protective equipment such as chemical goggles and gloves should be worn. Avoid inhaling its vapors or touching the skin. During operation, it should be carried out in a well-ventilated area to avoid contact with oxidants and combustibles. When stored, it should be sealed in a cool and dry place, away from open flames and heat sources.
1,3-thiazole-2-carbonyl chloride is an important organic synthesis intermediate. It is commonly used in the synthesis of pharmaceuticals, pesticides, dyes and other organic compounds. It is often used in drug research to synthesize antibiotics, anticancer drugs, antiviral drugs, etc. In addition, it can also be used to synthesize biologically active molecules and functional materials.
The method for preparing 1,3-thiazole-2-carbonyl chloride is usually obtained by reacting 1,3-thiazole-2-formyloxime with thionyl chloride. This reaction is carried out at room temperature using thionyl chloride as a reaction solvent.
Pay attention to safety when using and storing 1,3-thiazole-2-carbonyl chloride. Appropriate personal protective equipment such as chemical goggles and gloves should be worn. Avoid inhaling its vapors or touching the skin. During operation, it should be carried out in a well-ventilated area to avoid contact with oxidants and combustibles. When stored, it should be sealed in a cool and dry place, away from open flames and heat sources.
Last Update：2024-04-09 20:52:54
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