304445-49-6
1-(4-bromo-3-fluorophenyl)ethanone
CAS: 304445-49-6
Molecular Formula: C8H6BrFO
304445-49-6 - Names and Identifiers
304445-49-6 - Physico-chemical Properties
| Molecular Formula | C8H6BrFO |
| Molar Mass | 217.04 |
| Density | 1.535 |
| Boling Point | 263.3℃ |
| Flash Point | 113.0℃ |
| Vapor Presure | 0.0104mmHg at 25°C |
| Appearance | Solid |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.534 |
304445-49-6 - Introduction
1-(4-bromo-3-fluorophenyl)ethanone, chemical formula C8H6BrFO, is an organic compound, prepared by the reaction of 3-fluoro-4-bromobenzene and ethyl acetate.
Its physical properties are colorless liquid, with chilli flavor and pungent odor. Insoluble in water at room temperature, soluble in a variety of organic solvents such as ethanol and dichloromethane.
1-(4-bromo-3-fluorophenyl)ethanone has a wide range of applications in the field of organic synthesis. It can be used as a substrate for glutarimide-like reactions in organic synthesis, participating in the reactions of imidization, imidization and Henbing-Luc acid. In addition, it can also be used to synthesize intermediates such as drugs and pesticides.
the method for preparing 1-(4-bromo-3-fluorophenyl)ethanone is generally to carry out esterification reaction of 3-fluoro-4-bromobenzene and ethyl acetate under suitable conditions to generate the target product and then to obtain it by purification.
During operation, you need to pay attention to the safety of 1-(4-bromo-3-fluorophenyl)ethanone. It is an irritating and corrosive compound that can cause irritation and burns on contact with the skin and eyes. Wear appropriate protective measures, such as gloves and goggles. At the same time, make sure to operate under well-ventilated conditions and avoid inhaling its vapors. In case of accidental ingestion or accidental exposure, seek medical attention immediately.
Its physical properties are colorless liquid, with chilli flavor and pungent odor. Insoluble in water at room temperature, soluble in a variety of organic solvents such as ethanol and dichloromethane.
1-(4-bromo-3-fluorophenyl)ethanone has a wide range of applications in the field of organic synthesis. It can be used as a substrate for glutarimide-like reactions in organic synthesis, participating in the reactions of imidization, imidization and Henbing-Luc acid. In addition, it can also be used to synthesize intermediates such as drugs and pesticides.
the method for preparing 1-(4-bromo-3-fluorophenyl)ethanone is generally to carry out esterification reaction of 3-fluoro-4-bromobenzene and ethyl acetate under suitable conditions to generate the target product and then to obtain it by purification.
During operation, you need to pay attention to the safety of 1-(4-bromo-3-fluorophenyl)ethanone. It is an irritating and corrosive compound that can cause irritation and burns on contact with the skin and eyes. Wear appropriate protective measures, such as gloves and goggles. At the same time, make sure to operate under well-ventilated conditions and avoid inhaling its vapors. In case of accidental ingestion or accidental exposure, seek medical attention immediately.
Last Update：2024-04-09 21:11:58
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View History
304445-49-6
1593-08-4
39742-60-4
10244-24-3
137159-36-5
Di(2-ethylhexyl)phosphoric acid
DIHYDROETHIDIUM
Methyl succinate
Niraparib Intermediate6
p-Anisaldehyde
1593-08-4
39742-60-4
10244-24-3
137159-36-5
Di(2-ethylhexyl)phosphoric acid
DIHYDROETHIDIUM
Methyl succinate
Niraparib Intermediate6
p-Anisaldehyde