32189-36-9
R-(-)-4-Chloromandelic acid
CAS: 32189-36-9
Molecular Formula: C8H7ClO3
32189-36-9 - Names and Identifiers
32189-36-9 - Physico-chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molar Mass | 186.59 |
| Density | 1.468 |
| Melting Point | 108°C |
| Boling Point | 361°C |
| Flash Point | 172°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 7.43E-06mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| BRN | 2692851 |
| pKa | 3.14±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.605 |
32189-36-9 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R41 - Risk of serious damage to eyes R42/43 - May cause sensitization by inhalation and skin contact. |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| WGK Germany | 3 |
32189-36-9 - Introduction
R-(-)-4-Chloromandelic acid, also known as (R-(-)-4-Chloromandelic acid, chemical formula C8H7ClO3, is an organic compound.
Nature:
R-(-)-4-Chloromandelic acid is a colorless crystalline solid with a special sour taste. It is stable at room temperature and sparingly soluble in water, but soluble in organic solvents such as ethanol, diethyl ether and dichloromethane.
Use:
R-(-)-4-Chloromandelic acid has important applications in drug synthesis. It can be used as a synthesis of biologically active molecules such as pharmaceutically active groups and intermediates.
Method:
R-(-)-4-Chloromandelic acid is usually prepared by optical separation or enzymatic catalysis. One common approach is to use stereoselective enzymes to catalyze the reaction such that only one chirality is retained in the product.
Safety Information:
R-(-)-4-Chloromandelic acid is relatively safe under correct use and storage. However, it is still a chemical and proper safe operating procedures should be followed. Exposure to R-(-)-4-Chloromandelic acid may cause irritation and allergic reactions, direct skin and eye contact should be avoided. Wear appropriate protective gloves and eye protection during use. If ingested or inhaled, seek medical help. During use and storage, keep away from flammable materials and strong oxidants, and ensure a well-ventilated working environment. Detailed safety information can be found in the relevant safety data sheet (SDS).
Nature:
R-(-)-4-Chloromandelic acid is a colorless crystalline solid with a special sour taste. It is stable at room temperature and sparingly soluble in water, but soluble in organic solvents such as ethanol, diethyl ether and dichloromethane.
Use:
R-(-)-4-Chloromandelic acid has important applications in drug synthesis. It can be used as a synthesis of biologically active molecules such as pharmaceutically active groups and intermediates.
Method:
R-(-)-4-Chloromandelic acid is usually prepared by optical separation or enzymatic catalysis. One common approach is to use stereoselective enzymes to catalyze the reaction such that only one chirality is retained in the product.
Safety Information:
R-(-)-4-Chloromandelic acid is relatively safe under correct use and storage. However, it is still a chemical and proper safe operating procedures should be followed. Exposure to R-(-)-4-Chloromandelic acid may cause irritation and allergic reactions, direct skin and eye contact should be avoided. Wear appropriate protective gloves and eye protection during use. If ingested or inhaled, seek medical help. During use and storage, keep away from flammable materials and strong oxidants, and ensure a well-ventilated working environment. Detailed safety information can be found in the relevant safety data sheet (SDS).
Last Update：2024-04-09 20:45:29
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