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3304-51-6

N-delta-cbz-L-ornithine

CAS: 3304-51-6

Molecular Formula: C13H18N2O4

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3304-51-6 - Names and Identifiers

Name N-delta-cbz-L-ornithine
Synonyms Orn(Z)
H-ORN(Z)-OH
H-Orn(Z)-OH
H-ORN(CBZ)-OH
L-Orn(Cbz)-OH
L-ORNITHINE(CBZ)
N5-Cbz-L-ornithine
N'-Cbz-L-Ornithine
N'-Cbz-L-ornithine
N-d-CBZ-L-Ornithine
N-delta-cbz-L-ornithine
N5-benzyloxycarbonyl-L-ornithine
N-5-BENZYLOXYCARBONYL-L-ORNITHINE
N~5~-[(benzyloxy)carbonyl]ornithine
N-?-CBZ-L-Ornithine N-?-Carbobenzyloxy-L-ornithine
(2S)-2-ammonio-5-{[(benzyloxy)carbonyl]amino}pentanoate
(2S)-2-amino-5-{[(benzyloxy)carbonyl]amino}pentanoic acid
CAS 3304-51-6
EINECS 221-980-8
InChI InChI=1/C13H18N2O4/c14-11(12(16)17)7-4-8-15-13(18)19-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9,14H2,(H,15,18)(H,16,17)/t11-/m0/s1

3304-51-6 - Physico-chemical Properties

Molecular FormulaC13H18N2O4
Molar Mass266.29
Density1.234±0.06 g/cm3(Predicted)
Melting Point248-252℃
Boling Point492.2±45.0 °C(Predicted)
Flash Point251.4°C
Solubility Acidic Alcohol (Sparingly), Aqueous Acid (Slightly)
Vapor Presure1.67E-10mmHg at 25°C
AppearanceSolid
ColorWhite
pKa2.51±0.24(Predicted)
Storage ConditionKeep in dark place,Inert atmosphere,2-8°C
Refractive Index1.556
MDLMFCD00037220

3304-51-6 - Risk and Safety

WGK Germany3

3304-51-6 - Reference Information

Application N'-Cbz-L-ornithine is an amino acid derivative that can be used as an intermediate in organic synthesis and a pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
preparation to L-ornithine hydrochloride (5.0g,29.7mmol) in aqueous sodium hydroxide solution (50ml, 0.5M) to this solution was added a solution of copper sulfate (17.8g, mmol) in water (ml), and the mixture was stirred at room temperature for 4 hours. The mixture was then cooled to 0 °c before sodium bicarbonate (5.0g,59.4mmol) and benzyl chloroformate (5.7mL,40.1mmol) were added. The pH was then adjusted to pH

9 by careful addition of aqueous sodium hydroxide (1.0M) and the mixture was stirred at room temperature for 4 hours. The resulting solid was collected by filtration, washed with water, then ether, dissolved in aqueous EDTA (0.5 ml, M) and stirred vigorously at room temperature for 14 hours. The solid was again collected by filtration and washed with water to give crude solid N'-Cbz-L-ornithine, which was used without further purification.
Last Update:2024-04-09 15:16:40
3304-51-6
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