334769-80-1

334769-80-1 - Names and Identifiers

Name	(2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
Synonyms	GS-5817 interMediate Boc-cis-5-methyl-Pro-OH (2S,5S)-Boc-5-methylpyrrolidine-2-carboxylic acid (2S,5S)-N-Boc-5-Methylpyrrolidine-2-carboxylic aci (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid cis-5-Methyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester (2S,5S)-1-(tert-Butoxycarbonyl)-5-methylpyrrolidine-2-carboxylic acid 2. (2S,5S)-1-(tert-butoxycarbonyl)-5-methylpyrrolidine-2-carboxylic acid (2S,5S)- 5-Methyl-1,2-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester (2S,5S)-5-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid(2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
CAS	334769-80-1
InChI	InChI=1/C11H19NO4/c1-7-5-6-8(9(13)14)12(7)10(15)16-11(2,3)4/h7-8H,5-6H2,1-4H3,(H,13,14)/t7-,8-/m0/s1

334769-80-1 - Physico-chemical Properties

Molecular Formula	C11H19NO4
Molar Mass	229.27
Density	1.150
Boling Point	343.2±35.0 °C(Predicted)
pKa	4.02±0.40(Predicted)
Storage Condition	2-8°C
Refractive Index	1.49

334769-80-1 - Introduction

(2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is an organic compound, also known as (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid
-molecular formula: C11H19NO4
-Molecular weight: 233.27g/mol
-Melting Point: 75-77 ℃
-Solubility: Soluble in common organic solvents such as ethanol, chloroform, dichloromethane

Use:
- (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is usually used as a reagent for C- C bond formation reactions in organic synthesis, and has a catalytic effect.
-can be applied to the pharmaceutical field of drug development and synthesis.
-can be used to synthesize other organic compounds.

Method:
A commonly used method for preparing (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is to first use 5-methylpyrrolidine and N-tert-butoxycarbonyl-α-chloroacetamide as raw materials, the target product was synthesized under alkaline conditions.

Safety Information:
- (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is generally relatively safe under regular operating conditions, but the following matters still need to be paid attention:
-Avoid inhalation, contact with skin and eyes.
-Wear protective glasses and gloves during operation.
-Maintain good ventilation during operation.
-In case of contact, rinse immediately with plenty of water.
-Waste disposal is subject to local regulations.

Last Update：2024-04-09 02:00:45