343781-45-3
4-Bromo-3,5-dichloropyridine
CAS: 343781-45-3
Molecular Formula: C5H2BrCl2N
343781-45-3 - Names and Identifiers
| Name | 4-Bromo-3,5-dichloropyridine |
| Synonyms | T6NJ CG DE EG 4-Bromo-3,5-dichloropyridin 4-BROMO-3,5-DICHLOROPYRIDINE 4-Bromo-3,5-dichloropyridine 3,5-Dichloro-4-broMo-pyridine Pyridine, 4-bromo-3,5-dichloro- pyridine, 4-bromo-3,5-dichloro- |
| CAS | 343781-45-3 |
| InChI | InChI=1/C5H2BrCl2N/c6-5-3(7)1-9-2-4(5)8/h1-2H |
343781-45-3 - Physico-chemical Properties
| Molecular Formula | C5H2BrCl2N |
| Molar Mass | 226.89 |
| Density | 1.848g/cm3 |
| Melting Point | 75-76℃ |
| Boling Point | 250.655°C at 760 mmHg |
| Flash Point | 105.393°C |
| Vapor Presure | 0.034mmHg at 25°C |
| Appearance | Solid |
| Color | Off-white |
| Storage Condition | Room Temprature |
| Refractive Index | 1.597 |
343781-45-3 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
343781-45-3 - Introduction
4-Bromo-3,5-dichloropyridine is an organic compound with the chemical formula C5H2BrCl2N. The following is a description of its nature, use, preparation and safety information:
Nature:
4-Bromo-3,5-dichloropyridine is a colorless or pale yellow crystal with a special aromatic odor. Its melting point is between 80-82°C and its boiling point is between 289-290°C. It is insoluble in water at normal temperature, but soluble in organic solvents such as ethanol and chloroform.
Use:
4-Bromo-3,5-dichloropyridine is widely used in the chemical industry. It is an important intermediate of pyridine compounds and can be used in the synthesis of other organic compounds and drugs. It has good chemical stability and reactivity, and can be used as a catalyst, ligand, dye and pesticide raw materials.
Preparation Method:
The preparation method of 4-Bromo-3,5-dichloropyridine is generally achieved by the substitution reaction of pyridine. The commonly used preparation method includes the reaction of pyridine with bromine and ferric chloride, and the substitution reaction is carried out under appropriate conditions to obtain the target product. The preparation process needs to control the reaction temperature, pH value and reaction time and other parameters to obtain high purity products.
Safety Information:
4-Bromo-3,5-dichloropyridine is a relatively stable and safe compound under general conditions, but it is still necessary to pay attention to safe operation. It can enter the body through inhalation, skin contact and ingestion. Inhalation of high concentrations of gases and dust can cause irritation, causing respiratory and eye discomfort. Contact with the skin can cause redness, tingling and allergic reactions. Ingestion of the compound may cause gastrointestinal discomfort and toxic effects. Therefore, appropriate protective equipment should be worn during use to avoid direct contact and inhalation. In case of accidents, emergency treatment should be carried out in time and professionals should be consulted. In addition, it should be stored in a dry, ventilated place, away from fire and oxidizing agents.
Nature:
4-Bromo-3,5-dichloropyridine is a colorless or pale yellow crystal with a special aromatic odor. Its melting point is between 80-82°C and its boiling point is between 289-290°C. It is insoluble in water at normal temperature, but soluble in organic solvents such as ethanol and chloroform.
Use:
4-Bromo-3,5-dichloropyridine is widely used in the chemical industry. It is an important intermediate of pyridine compounds and can be used in the synthesis of other organic compounds and drugs. It has good chemical stability and reactivity, and can be used as a catalyst, ligand, dye and pesticide raw materials.
Preparation Method:
The preparation method of 4-Bromo-3,5-dichloropyridine is generally achieved by the substitution reaction of pyridine. The commonly used preparation method includes the reaction of pyridine with bromine and ferric chloride, and the substitution reaction is carried out under appropriate conditions to obtain the target product. The preparation process needs to control the reaction temperature, pH value and reaction time and other parameters to obtain high purity products.
Safety Information:
4-Bromo-3,5-dichloropyridine is a relatively stable and safe compound under general conditions, but it is still necessary to pay attention to safe operation. It can enter the body through inhalation, skin contact and ingestion. Inhalation of high concentrations of gases and dust can cause irritation, causing respiratory and eye discomfort. Contact with the skin can cause redness, tingling and allergic reactions. Ingestion of the compound may cause gastrointestinal discomfort and toxic effects. Therefore, appropriate protective equipment should be worn during use to avoid direct contact and inhalation. In case of accidents, emergency treatment should be carried out in time and professionals should be consulted. In addition, it should be stored in a dry, ventilated place, away from fire and oxidizing agents.
Last Update：2024-04-09 20:52:54
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