35264-07-4
boc-L-alloisoleucine
CAS: 35264-07-4
Molecular Formula: C11H21NO4
35264-07-4 - Names and Identifiers
35264-07-4 - Physico-chemical Properties
| Molecular Formula | C11H21NO4 |
| Molar Mass | 231.29 |
| Density | 1.061±0.06 g/cm3(Predicted) |
| Melting Point | 60-64°C |
| Boling Point | 356.0±25.0 °C(Predicted) |
| BRN | 2212874 |
| pKa | 4.03±0.22(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
35264-07-4 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
35264-07-4 - Introduction
boc-L-alloisoleucine is an amino acid containing a protecting group (boc). Its chemical name is (2S,3S)-2-amino-3-methylpentanoic acid. Its molecular formula is C9H19NO4 and its molecular weight is 201.25. It is a derivative of isoleucine (alloisoleucine).
boc-L-alloisoleucine are commonly used in the field of organic synthesis and drug development. Because its structure contains protecting groups, it can be used for the introduction and modification of synthetic polypeptides or proteins. In peptide synthesis, it is often used as a carbonyl protecting group to prevent undesired reactions of other functional groups. In addition, it can also be used as a chiral intermediate to participate in the synthesis of chiral organic compounds.
The preparation method of boc-L-alloisoleucine includes drum-catalyzed asymmetric hydrogenation in the form of aniline. First, isoleucine is reacted with the protecting group boc to give boc-isoleucine. Then, boc-isoleucine was subjected to asymmetric hydrogenation reaction using a drum catalyst to obtain boc-L-alloisoleucine.
For safety information, the specific physical and chemical properties of boc-L-alloisoleucine may make them skin, eye and respiratory tract irritants. Therefore, when in contact with the compound at work, appropriate personal protective measures should be taken, such as wearing protective glasses, gloves and protective masks. In addition, the compound should be kept safe to avoid storage and contact with oxidants and combustibles. Good laboratory safety practices must be followed when using or handling the compound.
boc-L-alloisoleucine are commonly used in the field of organic synthesis and drug development. Because its structure contains protecting groups, it can be used for the introduction and modification of synthetic polypeptides or proteins. In peptide synthesis, it is often used as a carbonyl protecting group to prevent undesired reactions of other functional groups. In addition, it can also be used as a chiral intermediate to participate in the synthesis of chiral organic compounds.
The preparation method of boc-L-alloisoleucine includes drum-catalyzed asymmetric hydrogenation in the form of aniline. First, isoleucine is reacted with the protecting group boc to give boc-isoleucine. Then, boc-isoleucine was subjected to asymmetric hydrogenation reaction using a drum catalyst to obtain boc-L-alloisoleucine.
For safety information, the specific physical and chemical properties of boc-L-alloisoleucine may make them skin, eye and respiratory tract irritants. Therefore, when in contact with the compound at work, appropriate personal protective measures should be taken, such as wearing protective glasses, gloves and protective masks. In addition, the compound should be kept safe to avoid storage and contact with oxidants and combustibles. Good laboratory safety practices must be followed when using or handling the compound.
Last Update：2024-04-09 21:04:16
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