357263-48-0
7-chloro-1H-pyrrolo[3,2-b]pyridine
CAS: 357263-48-0
Molecular Formula: C7H5ClN2
357263-48-0 - Names and Identifiers
| Name | 7-chloro-1H-pyrrolo[3,2-b]pyridine |
| Synonyms | 7-Chloro-4-azaindole 7-chloro-1H-pyrrolo[3 7-Chloro-4-azaindole 7- 7-Chloro-1H-pyrrolo[3,2-b... 7-chloro-1H-pyrrolo[3,2-b]pyridine 7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE 1H-pyrrolo[3,2-b]pyridine, 7-chloro- 1H-Pyrrolo[3,2-b]pyridine, 7-chloro- |
| CAS | 357263-48-0 |
| InChI | InChI=1/C7H5ClN2/c8-5-1-3-9-6-2-4-10-7(5)6/h1-4,10H |
357263-48-0 - Physico-chemical Properties
| Molecular Formula | C7H5ClN2 |
| Molar Mass | 152.58 |
| Density | 1.425 |
| Boling Point | 290.6±20.0 °C(Predicted) |
| Flash Point | 157.181°C |
| Vapor Presure | 0.004mmHg at 25°C |
| Appearance | Solid |
| pKa | 13.08±0.40(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.703 |
357263-48-0 - Introduction
7-chloro-1H-pyrrolo[3,2-b]pyridine is an organic compound with the chemical formula C8H5ClN. It is a yellow crystal or light yellow solid with a special aromatic odor.
Regarding its properties, 7-chloro-1H-prrolo [3,2-b]pyridine is stable at room temperature and insoluble in water, but soluble in most organic solvents such as ethanol, dimethyl sulfoxide, etc. The melting point of this compound is about 124-126°C.
In application, 7-chloro-1H-pyrrolo[3,2-b]pyridine can be used as an important intermediate in organic synthesis. It has certain biological activity and is widely used in drug development, pesticide synthesis and other chemical fields.
With regard to its preparation, 7-chloro-1H-pyrrolo[3,2-b]pyridine can be prepared by different synthetic routes. Commonly used methods include using pyrrole-pyridine as a starting material to introduce chlorine atoms through chlorination or other synthetic methods, thereby obtaining the target product.
Safety precautions are required when using 7-chloroo-1H-pyrrolo [3,2-b]pyridine. Since it is an organic solvent-soluble compound, care should be taken to prevent skin contact, inhalation or ingestion. Appropriate protective equipment, including lab gloves, goggles, and lab coats, should be worn during laboratory operations. When handling the compound, it should be done in a well-ventilated environment to ensure safety. At the same time, please follow the correct operating procedures and safe operating instructions to use the compound.
Regarding its properties, 7-chloro-1H-prrolo [3,2-b]pyridine is stable at room temperature and insoluble in water, but soluble in most organic solvents such as ethanol, dimethyl sulfoxide, etc. The melting point of this compound is about 124-126°C.
In application, 7-chloro-1H-pyrrolo[3,2-b]pyridine can be used as an important intermediate in organic synthesis. It has certain biological activity and is widely used in drug development, pesticide synthesis and other chemical fields.
With regard to its preparation, 7-chloro-1H-pyrrolo[3,2-b]pyridine can be prepared by different synthetic routes. Commonly used methods include using pyrrole-pyridine as a starting material to introduce chlorine atoms through chlorination or other synthetic methods, thereby obtaining the target product.
Safety precautions are required when using 7-chloroo-1H-pyrrolo [3,2-b]pyridine. Since it is an organic solvent-soluble compound, care should be taken to prevent skin contact, inhalation or ingestion. Appropriate protective equipment, including lab gloves, goggles, and lab coats, should be worn during laboratory operations. When handling the compound, it should be done in a well-ventilated environment to ensure safety. At the same time, please follow the correct operating procedures and safe operating instructions to use the compound.
Last Update：2024-04-09 21:54:55
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