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35906-36-6

Onjisaponin B

CAS: 35906-36-6

Molecular Formula: C75H112O35

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35906-36-6 - Names and Identifiers

Name Onjisaponin B
Synonyms Sinegin 3
Senegin III
Onjisaponin B
Olean-12-ene-23,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, 28-[O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[O-β-D-galactopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→4)-6-deoxy-α-L-mannopyranosyl-(1→2)]-6-deoxy-4-O-[(2E)-3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]-β-D-galactopyranosyl] ester, (2β,3β,...
CAS 35906-36-6

35906-36-6 - Physico-chemical Properties

Molecular FormulaC75H112O35
Molar Mass1573.67
Density1.54±0.1 g/cm3 (20 ºC 760 Torr)
Melting Point254-256°C
Specific Rotation(α)-10.2 (c, 1.08 in MeOH)
Solubility Soluble in water, ethanol, methanol and other solvents, insoluble in petroleum ether, chloroform, ethyl acetate.
AppearanceWhite needle crystal
pKa4.14±0.70(Predicted)
Storage Condition2-8℃
SensitiveEasily absorbing moisture
MDLMFCD28124358
Physical and Chemical PropertiesWhite crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Willd, Polygala tenuifolia of Polygala tenuifolia..

35906-36-6 - Reference

Reference
Show more
1. [IF=3.935] Ruimei Lin et al."Global identification and determination of the major constituents in Kai-Xin-San by ultra-performance liquid chromatography-quadrupole-Orbitrap mass spectrometry and gas chromatography-mass spectrometry."J Pharmaceut Biomed. 2021 Nov;206

35906-36-6 - Introduction

Onjisaponin B is an active ingredient extracted from the traditional Chinese medicine Polygala. Its chemical structure is protocatechol structure with multiple biological activities. The common properties of Onjisaponin B are as follows:

1. Water solubility: Onjisaponin B is easily soluble in water and can be dissolved under appropriate conditions.

2. Biological activity: Onjisaponin B has antioxidant, anti-inflammatory, antibacterial, anti-tumor and other biological activities, has a certain health and medicinal value.

The use of Onjisaponin B mainly includes the following aspects:

1. Medicinal: Onjisaponin B can be used as the main active ingredient of Chinese medicine Polygala, used to treat digestive system diseases, nervous system diseases, cardiovascular diseases, etc.

2. Health care products: Onjisaponin B is often used to make health care products, with anti-aging, improve immunity, antioxidant and other effects.

The preparation method of Onjisaponin B generally adopts the method of separation and extraction. First, Polygala is ground into powder, and then its active ingredients are separated from other impurities by solvent extraction. In a specific operation, extraction can be performed using a solvent such as alcohols and ethers.

Regarding the safety information of Onjisaponin B, there is no clear report showing that it has significant toxic and side effects. But still need to pay attention to the following points when using:

1. Avoid excessive use: as far as possible in accordance with the doctor or health care products manufacturers recommended use, avoid more than the recommend dose.

2. Use with caution for those who are allergic: Some people may be allergic to Onjisaponin B, and pay attention to individual allergic reactions when using it.
Last Update:2024-04-10 22:40:09
35906-36-6
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