362469-45-2
(2-(trifluoromethyl)quinolin-4-yl)methanol
CAS: 362469-45-2
Molecular Formula: C11H8F3NO
362469-45-2 - Names and Identifiers
| Name | (2-(trifluoromethyl)quinolin-4-yl)methanol |
| Synonyms | 4-Quinolinemethanol, 2-(trifluoromethyl)- (2-(Trifluoromethyl)quinolin-4-yl)methanol (2-(trifluoromethyl)quinolin-4-yl)methanol |
| CAS | 362469-45-2 |
362469-45-2 - Physico-chemical Properties
| Molecular Formula | C11H8F3NO |
| Molar Mass | 227.18 |
| Density | 1.384±0.06 g/cm3(Predicted) |
| Boling Point | 307.8±37.0 °C(Predicted) |
| pKa | 13.13±0.10(Predicted) |
362469-45-2 - Risk and Safety
| Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36/37 - Wear suitable protective clothing and gloves. |
| HS Code | 29334900 |
362469-45-2 - Introduction
(2-(trifluoromethyl)quinolin-4-yl)methanol is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White solid
-Molecular formula: C11H8F3NO
-Molecular weight: 237.18g/mol
-Melting point: 80-82°C
-Boiling point: 297°C
Use:
(2-(trifluoromethyl)quinolin-4-yl)methanol catalysts and intermediates commonly used in organic synthesis. It can be used as a hydrogen donor or hydrogen acceptor in a variety of reactions, participating in redox reactions, carbonyl reduction reactions and cyclization reactions. At the same time, it can also be used as a synthetic intermediate for laser dyes and fluorescent labels.
Preparation Method:
The method for preparing (2-(trifluoromethyl)quinolin-4-yl)methanol is usually obtained by reacting (2-amino-quinolin-4-yl) carbaldehyde with trifluoromethanesulphuric acid. The reaction process undergoes the formation and shrinkage reaction of carbamic acid, and finally produces the target product.
Safety Information:
(2-(trifluoromethyl)quinolin-4-yl)methanol has limited toxicity information, but as an organic compound, the following safety precautions should be paid attention to when used:
-Avoid contact with skin and eyes, if accidental contact, rinse immediately with plenty of water.
-Do not inhale its vapor or dust, and ensure that it is operated in a well-ventilated place.
-Storage should be sealed and stored in a cool and dry place, away from fire and oxidizing agents.
-In use and handling, should follow the correct laboratory practice and personal protective measures.
Nature:
-Appearance: White solid
-Molecular formula: C11H8F3NO
-Molecular weight: 237.18g/mol
-Melting point: 80-82°C
-Boiling point: 297°C
Use:
(2-(trifluoromethyl)quinolin-4-yl)methanol catalysts and intermediates commonly used in organic synthesis. It can be used as a hydrogen donor or hydrogen acceptor in a variety of reactions, participating in redox reactions, carbonyl reduction reactions and cyclization reactions. At the same time, it can also be used as a synthetic intermediate for laser dyes and fluorescent labels.
Preparation Method:
The method for preparing (2-(trifluoromethyl)quinolin-4-yl)methanol is usually obtained by reacting (2-amino-quinolin-4-yl) carbaldehyde with trifluoromethanesulphuric acid. The reaction process undergoes the formation and shrinkage reaction of carbamic acid, and finally produces the target product.
Safety Information:
(2-(trifluoromethyl)quinolin-4-yl)methanol has limited toxicity information, but as an organic compound, the following safety precautions should be paid attention to when used:
-Avoid contact with skin and eyes, if accidental contact, rinse immediately with plenty of water.
-Do not inhale its vapor or dust, and ensure that it is operated in a well-ventilated place.
-Storage should be sealed and stored in a cool and dry place, away from fire and oxidizing agents.
-In use and handling, should follow the correct laboratory practice and personal protective measures.
Last Update：2024-04-10 22:29:15
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CAS: 362469-45-2
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