368890-20-4

368890-20-4 - Names and Identifiers

Name	5-(Difluoromethoxy)-2-{[4-chloro-3-methoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
Synonyms	5-(Difluoromethoxy)-2-{[4-chloro-3-methoxy-2-pyridinyl)methy... 5-DIFLUOROMETHOXY-2-[(4-CHLORO-3-METHOXY-2-PYRIDINYL)METHYL]THIO-1H-BENZIMIDAZOLE 5-Difluoromethoxy-2-[(4-Chloro-3-methoxy-2-pyridinyl)methyl]thio-1H-benzimidazole 2-[(4-chloro-3-methoxy-2-pyridinyl)methylthio]-6-(difluoromethoxy)-1H-benzimidazole 5-(Difluoromethoxy)-2-{[4-chloro-3-methoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole 5-(Difluoromethoxy)-2[[(4-chloro-3-methoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole 1H-Benzimidazole, 2-[[(4-chloro-3-methoxy-2-pyridinyl)methyl]thio]-6-(difluoromethoxy)- 2-(((4-Chloro-3-methoxypyridin-2-yl)methyl)thio)-6-(difluoromethoxy)-1H-benzo[d]imidazole 2-{[(4-chloro-3-methoxypyridin-2-yl)methyl]sulfanyl}-6-(difluoromethoxy)-1H-benzimidazole 2-(((4-Chloro-3-methoxypyridin-2-yl)methyl)thio)-5-(difluoromethoxy)-1H-benzo[d]imidazole
CAS	368890-20-4
EINECS	609-304-3
InChI	InChI=1/C15H12ClF2N3O2S/c1-22-13-9(16)4-5-19-12(13)7-24-15-20-10-3-2-8(23-14(17)18)6-11(10)21-15/h2-6,14H,7H2,1H3,(H,20,21)

368890-20-4 - Physico-chemical Properties

Molecular Formula	C15H12ClF2N3O2S
Molar Mass	371.79
Density	1.51±0.1 g/cm3(Predicted)
Boling Point	523.1±60.0 °C(Predicted)
Flash Point	270.163°C
Vapor Presure	0mmHg at 25°C
Appearance	Solid
pKa	8.96±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.644

368890-20-4 - Introduction

5-(Difluoromethoxy)-2-{[methyl]thio}-1H-benzimidazole is an organic compound with the chemical formula C14H10ClF2N3O2S.

Nature:
-Appearance: White or off-white crystalline solid.
-Melting point: about 180-185°C.
-Solubility: It can be dissolved in common organic solvents, such as ethanol and dimethyl sulfoxide.

Use:
This compound is often used as an intermediate in the synthesis of thioether heterocyclic compounds. It also has some applications in the field of drug research, where it is used to study and develop new drug molecules.

Preparation Method:
A commonly used preparation method is based on a nitrosone chemical reaction, reacting 1,3-dinitroarene with benzimidazole to generate an intermediate compound, followed by fluorination and methyl etherification to obtain the target product.

Safety Information:
Specific toxicity and safety information regarding this compound may require additional experimental data to be established. However, as an organic compound, it should generally be handled and handled with appropriate safety precautions, such as wearing appropriate protective gloves and eye protection, to avoid contact and inhalation. If there is any doubt, it is recommended to follow the relevant chemical safety data sheet for detailed understanding and operation.

Last Update：2024-04-09 20:45:29