369-03-9
6-fluoropyridine-2-carboxamide
CAS: 369-03-9
Molecular Formula: C6H5FN2O
369-03-9 - Names and Identifiers
369-03-9 - Physico-chemical Properties
| Molecular Formula | C6H5FN2O |
| Molar Mass | 140.12 |
| Density | 1.327±0.06 g/cm3(Predicted) |
| Melting Point | 134-137℃ |
| Boling Point | 287.9±25.0 °C(Predicted) |
| Flash Point | 127.9°C |
| Vapor Presure | 0.00242mmHg at 25°C |
| pKa | 14.53±0.50(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.542 |
369-03-9 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Note | Irritant |
369-03-9 - Introduction
It is an organic compound with a chemical formula of C6H4FN3O and a molecular weight of 153.12g/mol. Its nature is as follows:
1. Appearance: White solid.
2. melting point: about 157-158 degrees Celsius.
3. Solubility: Soluble in some organic solvents, such as ethanol, formic acid and dimethyl sulfoxide.
The main use of the formula is as an intermediate in organic synthesis reactions. It can be used to synthesize a variety of organic compounds, such as drugs, pesticides and dyes. In addition, it can also be used as a ligand for metal coordination compounds.
There are many ways to prepare, and the common methods include the following two:
1. Chemical synthesis: prepared by reacting 6-fluoropyridine with ammonia and formic acid.
2. redox method: 6-fluoropyridine-2-carboxylic acid is reduced to the corresponding alcohol, and then reacted with formamide to prepare it.
For safety information, specific toxicities and hazards have not been reported, but general precautions as organic compounds still apply. During operation, care should be taken to avoid direct contact with skin, eyes and respiratory tract. Use appropriate laboratory protective equipment, such as gloves, goggles and laboratory ventilation systems, to ensure safety. Follow proper chemical management practices when handling and storing, and keep them away from combustibles and strong oxidants.
Please note that the information provided above is for reference only, and the specific experimental operation and safety assessment should be carried out according to the specific situation and relevant literature.
1. Appearance: White solid.
2. melting point: about 157-158 degrees Celsius.
3. Solubility: Soluble in some organic solvents, such as ethanol, formic acid and dimethyl sulfoxide.
The main use of the formula is as an intermediate in organic synthesis reactions. It can be used to synthesize a variety of organic compounds, such as drugs, pesticides and dyes. In addition, it can also be used as a ligand for metal coordination compounds.
There are many ways to prepare, and the common methods include the following two:
1. Chemical synthesis: prepared by reacting 6-fluoropyridine with ammonia and formic acid.
2. redox method: 6-fluoropyridine-2-carboxylic acid is reduced to the corresponding alcohol, and then reacted with formamide to prepare it.
For safety information, specific toxicities and hazards have not been reported, but general precautions as organic compounds still apply. During operation, care should be taken to avoid direct contact with skin, eyes and respiratory tract. Use appropriate laboratory protective equipment, such as gloves, goggles and laboratory ventilation systems, to ensure safety. Follow proper chemical management practices when handling and storing, and keep them away from combustibles and strong oxidants.
Please note that the information provided above is for reference only, and the specific experimental operation and safety assessment should be carried out according to the specific situation and relevant literature.
Last Update：2024-04-09 20:52:54
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