371-14-2
4-fluorophenylhydrazine
CAS: 371-14-2
Molecular Formula: C6H7FN2
371-14-2 - Names and Identifiers
| Name | 4-fluorophenylhydrazine |
| Synonyms | AKOS BBS-00006439 4-Fluorophenylhydrazin 4-fluorophenylhydrazine 4-FLUOROPHENYLHYDRAZINE (4-fluorophenyl)hydrazine N-(4-Fluorophenyl)hydrazine 1-(4-Fluorophenyl)hydrazine 1-(4-FLUOROPHENYL)HYDRAZINE Hydrazine, (4-fluorophenyl)- |
| CAS | 371-14-2 |
| EINECS | 206-732-9 |
| InChI | InChI=1/C6H7FN2/c7-5-1-3-6(9-8)4-2-5/h1-4,9H,8H2 |
371-14-2 - Physico-chemical Properties
| Molecular Formula | C6H7FN2 |
| Molar Mass | 126.13 |
| Density | 1.257 |
| Melting Point | 36.8 °C |
| Boling Point | 227℃ |
| Flash Point | 91℃ |
| Vapor Presure | 0.0805mmHg at 25°C |
| pKa | 5.24±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.609 |
371-14-2 - Introduction
4-fluorophenylhydrazine is an organic compound with the chemical formula C6H6FN2, which is formed by replacing one hydrogen atom on the benzene ring with fluorine. The following is a description of the properties, uses, preparation and safety information of 4-fluorophenylhydrazine:
Nature:
-Appearance: 4-fluorophenylhydrazine is a colorless to pale yellow solid.
-Melting point and boiling point: The melting point is about 65-70 degrees Celsius, and the boiling point is 120 degrees Celsius.
-Solubility: Soluble in common organic solvents (such as ethanol, acetone, dimethylformamide).
Use:
- 4-fluorophenylhydrazine is commonly used as an amine protecting reagent, a nitrogen source or a condensation reagent in organic synthesis.
-It can be used to prepare laser materials, pesticides and pharmaceutical compounds.
Preparation Method:
The preparation of-4-fluorophenylhydrazine can be completed by the reaction of benzoic acid with ammonia hydrogen fluoride (HF/NH3). First, hydrogen peroxide is added to benzoic acid and hydrochloric acid solution to generate peroxybenzoic acid, and then hydrogen fluoride is added to ammonia to react to obtain 4-fluorophenylhydrazine.
Safety Information:
- 4-fluorophenylhydrazine is a toxic substance that may cause irritation and injury when inhaled or in contact with the skin. Therefore, appropriate protective equipment such as gloves and goggles should be worn during use.
-It should be stored in a dry, well-ventilated place, away from combustibles and oxidants.
-When handling 4-fluorophenylhydrazine, strictly follow safety procedures and ensure that reactions with other chemicals are avoided.
Nature:
-Appearance: 4-fluorophenylhydrazine is a colorless to pale yellow solid.
-Melting point and boiling point: The melting point is about 65-70 degrees Celsius, and the boiling point is 120 degrees Celsius.
-Solubility: Soluble in common organic solvents (such as ethanol, acetone, dimethylformamide).
Use:
- 4-fluorophenylhydrazine is commonly used as an amine protecting reagent, a nitrogen source or a condensation reagent in organic synthesis.
-It can be used to prepare laser materials, pesticides and pharmaceutical compounds.
Preparation Method:
The preparation of-4-fluorophenylhydrazine can be completed by the reaction of benzoic acid with ammonia hydrogen fluoride (HF/NH3). First, hydrogen peroxide is added to benzoic acid and hydrochloric acid solution to generate peroxybenzoic acid, and then hydrogen fluoride is added to ammonia to react to obtain 4-fluorophenylhydrazine.
Safety Information:
- 4-fluorophenylhydrazine is a toxic substance that may cause irritation and injury when inhaled or in contact with the skin. Therefore, appropriate protective equipment such as gloves and goggles should be worn during use.
-It should be stored in a dry, well-ventilated place, away from combustibles and oxidants.
-When handling 4-fluorophenylhydrazine, strictly follow safety procedures and ensure that reactions with other chemicals are avoided.
Last Update：2024-04-09 21:01:54
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