37239-51-3
Wtlfordine
CAS: 37239-51-3
Molecular Formula: C43H49NO19
37239-51-3 - Names and Identifiers
37239-51-3 - Physico-chemical Properties
| Molecular Formula | C43H49NO19 |
| Molar Mass | 883.85 |
| Density | 1.44±0.1 g/cm3(Predicted) |
| Melting Point | 175-6°C |
| Boling Point | 895.5±65.0 °C(Predicted) |
| Solubility | Soluble in alkali, glacial acetic acid, pyridine, slightly soluble in general organic solvents, hardly soluble in water. |
| Appearance | White powder |
| pKa | 11.63±0.70(Predicted) |
| Storage Condition | 2-8℃ |
37239-51-3 - Introduction
Tripterygium wilfordii (Tripterygium wilfordii) is a common Chinese herbal plant, its root bark contains the main active ingredients Triptolide (Triptolide) and Wtlfordine(Wilforgine), wherein Wtlfordine is a compound with pharmacological activity.
Wtlfordine is a basic compound with a four-ring two-ring lactone ring structure. It has anti-inflammatory, immunosuppressive, anti-tumor and other pharmacological activities. In laboratory studies, Wtlfordine has been shown to suppress inflammatory responses, immune cell activation, and glucocorticoid-induced immunosuppression.
Wtlfordine is very versatile. In traditional Chinese medicine, Tripterygium wilfordii is used to treat autoimmune diseases such as rheumatoid arthritis, gout and systemic lupus erythematosus. In addition, Wtlfordine has also been studied for use in areas such as anti-tumor therapy and immunomodulation.
The preparation method of Wtlfordine is mainly obtained by extraction, separation and purification. Usually, an alcohol solvent such as an alcohol-water mixture is used to obtain an extract from the root bark of Tripterygium wilfordii through steps such as extraction, filtration and concentration, and then pure Wtlfordine is prepared by crystallization, washing and drying.
When using Wtlfordine, you need to pay attention to its safety. Wtlfordine is a compound with strong toxicity and a certain danger to the human body. During use and handling, strict protective measures should be taken, such as wearing protective gloves and glasses that meet safety standards, and maintaining good ventilation conditions. In addition, Wtlfordine should not be used for pregnant women, lactating women and patients with liver and kidney damage. In use, should be strictly in accordance with the guidance of doctors or experts for medication.
Wtlfordine is a basic compound with a four-ring two-ring lactone ring structure. It has anti-inflammatory, immunosuppressive, anti-tumor and other pharmacological activities. In laboratory studies, Wtlfordine has been shown to suppress inflammatory responses, immune cell activation, and glucocorticoid-induced immunosuppression.
Wtlfordine is very versatile. In traditional Chinese medicine, Tripterygium wilfordii is used to treat autoimmune diseases such as rheumatoid arthritis, gout and systemic lupus erythematosus. In addition, Wtlfordine has also been studied for use in areas such as anti-tumor therapy and immunomodulation.
The preparation method of Wtlfordine is mainly obtained by extraction, separation and purification. Usually, an alcohol solvent such as an alcohol-water mixture is used to obtain an extract from the root bark of Tripterygium wilfordii through steps such as extraction, filtration and concentration, and then pure Wtlfordine is prepared by crystallization, washing and drying.
When using Wtlfordine, you need to pay attention to its safety. Wtlfordine is a compound with strong toxicity and a certain danger to the human body. During use and handling, strict protective measures should be taken, such as wearing protective gloves and glasses that meet safety standards, and maintaining good ventilation conditions. In addition, Wtlfordine should not be used for pregnant women, lactating women and patients with liver and kidney damage. In use, should be strictly in accordance with the guidance of doctors or experts for medication.
Last Update：2024-04-09 20:52:54
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View History
37239-51-3
34097-16-0
117-62-4
37148-27-9
Chavicol
EOS-60654
4-HYDROXYBENZOIC ACID-RING-UL-14C
Vassgro mini slug pellets
Boron tribromide dimethyl sulfide complex
2-AMINOETHYL ISOPROPYL ETHER
34097-16-0
117-62-4
37148-27-9
Chavicol
EOS-60654
4-HYDROXYBENZOIC ACID-RING-UL-14C
Vassgro mini slug pellets
Boron tribromide dimethyl sulfide complex
2-AMINOETHYL ISOPROPYL ETHER