374898-01-8
(R)-1-(4-Fluorophenyl)ethylamine
CAS: 374898-01-8
Molecular Formula: C8H10FN
374898-01-8 - Names and Identifiers
374898-01-8 - Physico-chemical Properties
| Molecular Formula | C8H10FN |
| Molar Mass | 139.17 |
| Density | 1,03 g/cm3 |
| Melting Point | -30°C |
| Boling Point | 76°C 22mm |
| Flash Point | 76°C/22mm |
| Water Solubility | Sparingly Soluble in water (1.5E-3 g/L) (25°C). |
| Vapor Presure | 0.698mmHg at 25°C |
| BRN | 8614058 |
| pKa | 8.98±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Air Sensitive |
| Refractive Index | 1.501 |
| MDL | MFCD03093090 |
374898-01-8 - Risk and Safety
| Risk Codes | R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 2735 |
| WGK Germany | 3 |
| HS Code | 29214990 |
| Hazard Note | Irritant |
| Hazard Class | 8 |
| Packing Group | III |
374898-01-8 - Introduction
(R)-1-(4-Fluorophenyl)ethylamine is an organic compound with the chemical formula C8H10FN and a molecular weight of 137.17g/mol. The compound is chiral and has optical properties, specifically the dextrorotatory () isomer.
Nature:
(R)-1-(4-Fluorophenyl)ethylamine is a colorless to pale yellow liquid with a distinctive ammonia-like aroma. It has strong hydrophilicity and can be miscible with water or organic solvents.
Use:
(R)-1-(4-Fluorophenyl)ethylamine is commonly used in asymmetric synthesis reactions in organic synthesis. It can be used as a chiral ligand or chiral inducer, and is widely used in pharmaceutical synthesis, materials science, pesticides and spices.
Preparation Method:
(R)-1-(4-Fluorophenyl)ethylamine is prepared by a variety of methods. The common method is to Grignard boric acid o-fluorophenyl formate and propyl magnesium bromide, and then to convert the corresponding functional groups.
Safety Information:
(R)-1-(4-Fluorophenyl)ethylamine is stable under normal conditions, but is a flammable liquid. Use should pay attention to fire and explosion prevention measures. In addition, contact with strong oxidants, strong acids and strong bases should be avoided. For humans, there is still a lack of relevant toxicity research data, so appropriate protective measures should be taken during contact or use, such as wearing respiratory protective equipment and chemical protective gloves. In case of accidental exposure or ingestion, seek medical attention immediately.
Nature:
(R)-1-(4-Fluorophenyl)ethylamine is a colorless to pale yellow liquid with a distinctive ammonia-like aroma. It has strong hydrophilicity and can be miscible with water or organic solvents.
Use:
(R)-1-(4-Fluorophenyl)ethylamine is commonly used in asymmetric synthesis reactions in organic synthesis. It can be used as a chiral ligand or chiral inducer, and is widely used in pharmaceutical synthesis, materials science, pesticides and spices.
Preparation Method:
(R)-1-(4-Fluorophenyl)ethylamine is prepared by a variety of methods. The common method is to Grignard boric acid o-fluorophenyl formate and propyl magnesium bromide, and then to convert the corresponding functional groups.
Safety Information:
(R)-1-(4-Fluorophenyl)ethylamine is stable under normal conditions, but is a flammable liquid. Use should pay attention to fire and explosion prevention measures. In addition, contact with strong oxidants, strong acids and strong bases should be avoided. For humans, there is still a lack of relevant toxicity research data, so appropriate protective measures should be taken during contact or use, such as wearing respiratory protective equipment and chemical protective gloves. In case of accidental exposure or ingestion, seek medical attention immediately.
Last Update：2024-04-09 20:52:54
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