38861-78-8
4-Isobutylacetophenone
CAS: 38861-78-8
Molecular Formula: C12H16O
38861-78-8 - Names and Identifiers
| Name | 4-Isobutylacetophenone |
| Synonyms | IBUPROFEN IMP E TIMTEC-BB SBB007668 IBUPROFEN IMPURITY E ISOBUTYL ACETOPHENONE 4-Isobutylacetaphenone 4-Isobutylacetophenone P-ISO-BUTYLACETOPHENONE 4'-ISOBUTYLACETOPHENONE 4-methyl-3-phenylpentan-2-one 4'-(2-Methylpropyl)Acetophenone 1-[4-(2-METHYLPROPYL)PHENYL]ETHANONE |
| CAS | 38861-78-8 |
| EINECS | 254-159-8 |
| InChI | InChI=1/C12H16O/c1-9(2)12(10(3)13)11-7-5-4-6-8-11/h4-9,12H,1-3H3 |
38861-78-8 - Physico-chemical Properties
| Molecular Formula | C12H16O |
| Molar Mass | 176.25 |
| Density | 0,952 g/cm3 |
| Boling Point | 134-135°C 16mm |
| Flash Point | 54°C |
| Water Solubility | Miscible with chloroform and methanol. Slightly miscible with water. |
| Vapor Presure | 0.75Pa at 20℃ |
| Appearance | neat |
| Color | Colorless to Yellow |
| BRN | 1935275 |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.5180 |
| Physical and Chemical Properties | Liquid. Boiling point 124-130 deg C (1.33kPa). |
38861-78-8 - Risk and Safety
| Risk Codes | R10 - Flammable R40 - Limited evidence of a carcinogenic effect R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R43 - May cause sensitization by skin contact |
| Safety Description | S16 - Keep away from sources of ignition. S36 - Wear suitable protective clothing. S22 - Do not breathe dust. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | 1224 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29143990 |
| Hazard Class | 3.2 |
| Packing Group | III |
38861-78-8 - Nature
Open Data Verified Data
liquid, boiling point 124~130 ℃(1. 33kPa).
Last Update：2024-01-02 23:10:35
38861-78-8 - Preparation Method
Open Data Verified Data
prepared by the reaction of isobutylbenzene with acetyl chloride.
Last Update：2022-01-01 10:42:32
38861-78-8 - Application
Open Data Verified Data
in medicine for the synthesis of antipyretic analgesic drugs such as ibuprofen.
Last Update：2025-08-19 16:24:40
38861-78-8 - Reference Information
| LogP | 3.4 at 23℃ |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| use | used in medicine to synthesize antipyretic analgesic ibuprofen, etc. |
| Production method | The reaction of toluene and propylene with the participation of potassium metal, sodium carbonate and graphite, the methyl group is alkylated to produce isobutylbenzene, and then acetyl chloride is acetylated with the participation of anhydrous aluminum trichloride to prepare the product. |
Last Update：2024-04-09 02:00:08
Supplier List
Featured ProductsSpot supply
Product Name: 4'-(2-Methylpropyl)acetophenone Visit Supplier Webpage Request for quotationCAS: 38861-78-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-Isobutylacetophenone Request for quotationCAS: 38861-78-8
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Product Name: 4-Isobutylacetophenone Request for quotation
CAS: 38861-78-8
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 38861-78-8
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 1-(4-isobutylphenyl)ethan-1-one Request for quotationCAS: 38861-78-8
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249
Wechat: 15787876101
Spot supply
Product Name: 4-Isobutylacetophenone Request for quotationCAS: 38861-78-8
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 4'-Isobutylacetophenone Request for quotationCAS: 38861-78-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4'-(2-Methylpropyl)acetophenone Visit Supplier Webpage Request for quotationCAS: 38861-78-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4'-Isobutylacetophenone (Standard) Visit Supplier Webpage Request for quotationCAS: 38861-78-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 4'-Isobutylacetophenone Visit Supplier Webpage Request for quotationCAS: 38861-78-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 4-Isobutylacetophenone Request for quotation
CAS: 38861-78-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 38861-78-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Featured ProductsSpot supply
Product Name: 4'-(2-Methylpropyl)acetophenone Visit Supplier Webpage Request for quotationCAS: 38861-78-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-Isobutylacetophenone Request for quotationCAS: 38861-78-8
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Product Name: 4-Isobutylacetophenone Request for quotation
CAS: 38861-78-8
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 38861-78-8
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 1-(4-isobutylphenyl)ethan-1-one Request for quotationCAS: 38861-78-8
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249
Wechat: 15787876101
Spot supply
Product Name: 4-Isobutylacetophenone Request for quotationCAS: 38861-78-8
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 4'-Isobutylacetophenone Request for quotationCAS: 38861-78-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4'-(2-Methylpropyl)acetophenone Visit Supplier Webpage Request for quotationCAS: 38861-78-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4'-Isobutylacetophenone (Standard) Visit Supplier Webpage Request for quotationCAS: 38861-78-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 4'-Isobutylacetophenone Visit Supplier Webpage Request for quotationCAS: 38861-78-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 4-Isobutylacetophenone Request for quotation
CAS: 38861-78-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 38861-78-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
View History