4-(2-Fluoro-4-nitrophenyl)morpholine
4-(2-Fluoro-4-nitrophenyl)morpholine
CAS: 2689-39-6
Molecular Formula: C10H11FN2O3
4-(2-Fluoro-4-nitrophenyl)morpholine - Names and Identifiers
| Name | 4-(2-Fluoro-4-nitrophenyl)morpholine |
| Synonyms | Linezolid Impurity 27 Linezolid Impurity 12 4-(2-fluoro-nitrophenyl)Morpholine N-(2-Fluoro-4-nitrophenyl)morpholine 4-(2-Fluoro-4-nitrophenyl)morpholine 4-(2-Fluoro-4-Nitro-Phenyl)-Morpholine 3-fluoro-4-(4-morpholinyl)nitrobenzene 4-(2-FLUORO-4-NITRO-PHENYL)-MORPHOLINE 4-(2-fluoro-4-nitrophenyl) Moropholine Morpholine, 4-(2-fluoro-4-nitrophenyl)- 3-Fluoro-4-(4-morpholinyl) nitrobenzene (FMN) |
| CAS | 2689-39-6 |
| EINECS | 1592732-453-0 |
| InChI | InChI=1/C10H11FN2O3/c11-9-7-8(13(14)15)1-2-10(9)12-3-5-16-6-4-12/h1-2,7H,3-6H2 |
4-(2-Fluoro-4-nitrophenyl)morpholine - Physico-chemical Properties
| Molecular Formula | C10H11FN2O3 |
| Molar Mass | 226.2 |
| Density | 1.340±0.06 g/cm3(Predicted) |
| Melting Point | 121-126℃ |
| Boling Point | 380.9±42.0 °C(Predicted) |
| Flash Point | 184.2°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 5.26E-06mmHg at 25°C |
| Appearance | Solid |
| Color | Yellow to Orange |
| pKa | 0.62±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.56 |
4-(2-Fluoro-4-nitrophenyl)morpholine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
4-(2-Fluoro-4-nitrophenyl)morpholine - Introduction
4-(2-Fluoro-4-nitrophenyl)morpholine is an organic compound with the chemical formula C10H10FNO3. Its structure contains a 4-morpholinobenzene ring with fluorine atoms and nitro groups substituted on the benzene ring.
Nature:
4-(2-Fluoro-4-nitrophenyl)morpholine is a white crystal or crystalline powder with a high melting point and boiling point. It is almost insoluble in water at normal temperature, but soluble in organic solvents such as ethanol, dimethyl ether and methylene chloride. It is a stable compound that does not readily decompose or degrade under normal storage conditions.
Use:
4-(2-Fluoro-4-nitrophenyl)morpholine is commonly used as an intermediate in organic synthesis and has important applications in the synthesis of pesticides and drugs. It can also be used in the production of chemicals for the dye, photosensitizer and rubber industries. In addition, it can also be used as a raw material for the synthesis of organic materials.
Method:
The preparation of 4-(2-Fluoro-4-nitrophenyl)morpholine can usually be obtained by reacting acetophenone with diethyl 3-fluoro-4-nitrophenylborate in the presence of an oxidizing agent.
Safety Information:
Since 4-(2-Fluoro-4-nitrophenyl)morpholine is an organic compound, it may cause certain harm to the human body. In use or operation, should strictly follow the relevant safety procedures, and take appropriate protective measures, such as wearing gloves, masks and protective glasses. Avoid contact with skin and eyes, and do not breathe its dust or gas. If you are exposed or ingested, you should seek medical treatment immediately and bring your safety data sheet with you for your doctor's reference.
Nature:
4-(2-Fluoro-4-nitrophenyl)morpholine is a white crystal or crystalline powder with a high melting point and boiling point. It is almost insoluble in water at normal temperature, but soluble in organic solvents such as ethanol, dimethyl ether and methylene chloride. It is a stable compound that does not readily decompose or degrade under normal storage conditions.
Use:
4-(2-Fluoro-4-nitrophenyl)morpholine is commonly used as an intermediate in organic synthesis and has important applications in the synthesis of pesticides and drugs. It can also be used in the production of chemicals for the dye, photosensitizer and rubber industries. In addition, it can also be used as a raw material for the synthesis of organic materials.
Method:
The preparation of 4-(2-Fluoro-4-nitrophenyl)morpholine can usually be obtained by reacting acetophenone with diethyl 3-fluoro-4-nitrophenylborate in the presence of an oxidizing agent.
Safety Information:
Since 4-(2-Fluoro-4-nitrophenyl)morpholine is an organic compound, it may cause certain harm to the human body. In use or operation, should strictly follow the relevant safety procedures, and take appropriate protective measures, such as wearing gloves, masks and protective glasses. Avoid contact with skin and eyes, and do not breathe its dust or gas. If you are exposed or ingested, you should seek medical treatment immediately and bring your safety data sheet with you for your doctor's reference.
Last Update：2024-04-09 21:04:16
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