4-Aminopiperidin-2-one
4-Amino-2-piperidinone
CAS: 5513-66-6
Molecular Formula: C5H10N2O
4-Aminopiperidin-2-one - Names and Identifiers
| Name | 4-Amino-2-piperidinone |
| Synonyms | A80265 4-aMino-2-Piperidino 4-AMino-2-piperidone 4-Aminopiperidin-2-on 4-Aminopiperidin-2-one 4-Amino-2-piperidinone 4-Amino-piperidin-2-one 2-piperidinone, 4-amino- 2-Piperidinone, 4-aMino- 4-Amino-2-piperidinone tr... 4-AMino-2-piperidinone hydrochloride 4-Amino-2-piperidinone trifluoroacetate |
| CAS | 5513-66-6 |
| InChI | InChI=1/C5H10N2O/c6-4-1-2-7-5(8)3-4/h4H,1-3,6H2,(H,7,8) |
4-Aminopiperidin-2-one - Physico-chemical Properties
| Molecular Formula | C5H10N2O |
| Molar Mass | 114.15 |
| Density | 1.071±0.06 g/cm3(Predicted) |
| Boling Point | 307.5±35.0 °C(Predicted) |
| Flash Point | 139.751°C |
| Vapor Presure | 0.001mmHg at 25°C |
| pKa | 16.10±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.477 |
4-Aminopiperidin-2-one - Introduction
4-Amino-2-piperidinone is an organic compound with the chemical formula C5H10N2O. The following is a description of its nature, use, preparation and safety information:
Nature:
4-Amino-2-piperidinone is colorless crystal or liquid form, with special amino and carbonyl functional groups. It is stable at room temperature, but may decompose when heated. It is soluble in solvents such as water, alcohols and ethers.
Use:
4-Amino-2-piperidinone is often used as an intermediate in organic synthesis. It can be used to prepare various important compounds, such as drugs, pesticides and dyes. Its amino and carbonyl groups can participate in a variety of reactions, such as aminocarboxylation, nucleophilic addition, and electrophilic substitution.
Preparation Method:
4-Amino-2-piperidinone is typically obtained by reacting cyclohexanone with an amino compound such as ammonia. The reaction is carried out under basic conditions and the product is purified by distillation. The specific reaction conditions and purification process can be adjusted according to specific experimental requirements.
Safety Information:
4-Amino-2-piperidinone is a chemical that should be handled with care. It should be kept away from fire and oxidizing agents and stored in a dry, cool place. Wear appropriate protective equipment such as goggles and gloves during use and handling. Before operation, the relevant safety technical instructions and operating instructions should be carefully read and understood. In case of skin contact or inhalation, the affected area should be cleaned promptly and medical help should be sought.
Nature:
4-Amino-2-piperidinone is colorless crystal or liquid form, with special amino and carbonyl functional groups. It is stable at room temperature, but may decompose when heated. It is soluble in solvents such as water, alcohols and ethers.
Use:
4-Amino-2-piperidinone is often used as an intermediate in organic synthesis. It can be used to prepare various important compounds, such as drugs, pesticides and dyes. Its amino and carbonyl groups can participate in a variety of reactions, such as aminocarboxylation, nucleophilic addition, and electrophilic substitution.
Preparation Method:
4-Amino-2-piperidinone is typically obtained by reacting cyclohexanone with an amino compound such as ammonia. The reaction is carried out under basic conditions and the product is purified by distillation. The specific reaction conditions and purification process can be adjusted according to specific experimental requirements.
Safety Information:
4-Amino-2-piperidinone is a chemical that should be handled with care. It should be kept away from fire and oxidizing agents and stored in a dry, cool place. Wear appropriate protective equipment such as goggles and gloves during use and handling. Before operation, the relevant safety technical instructions and operating instructions should be carefully read and understood. In case of skin contact or inhalation, the affected area should be cleaned promptly and medical help should be sought.
Last Update：2024-04-09 15:17:58
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