4-BENZYLBENZENESULFONAMIDE
4-BENZYLBENZENESULFONAMIDE
CAS: 1145-60-4
Molecular Formula: C13H13NO2S
4-BENZYLBENZENESULFONAMIDE - Names and Identifiers
| Name | 4-BENZYLBENZENESULFONAMIDE |
| Synonyms | 4-BENZYLBENZENESULFONAMIDE 4-Benzylbenzenesulfonamide 4-benzylbenzene-1-sulfonaMide benzenesulfonamide, 4-(phenylmethyl)- |
| CAS | 1145-60-4 |
| InChI | InChI=1/C13H13NO2S/c14-17(15,16)13-8-6-12(7-9-13)10-11-4-2-1-3-5-11/h1-9H,10H2,(H2,14,15,16) |
4-BENZYLBENZENESULFONAMIDE - Physico-chemical Properties
| Molecular Formula | C13H13NO2S |
| Molar Mass | 247.31 |
| Density | 1.25g/cm3 |
| Boling Point | 422.9°C at 760 mmHg |
| Flash Point | 209.5°C |
| Vapor Presure | 2.33E-07mmHg at 25°C |
| Refractive Index | 1.609 |
4-BENZYLBENZENESULFONAMIDE - Introduction
4-Benzylbenzenesulfonamide is an organic compound with the chemical formula C13H11NO2S. The following is an introduction to the properties, uses, preparation and safety information of 4-benzyl benzene sulfonamide:
Nature:
-Appearance: 4-Benzylbenzenesulfonamide is a white to slightly yellow crystalline powder.
-Melting point: Its melting point range is 121-123°C.
-Solubility: 4-benzyl benzene sulfonamide can be dissolved in most organic solvents, insoluble in water.
Use:
-Pharmaceuticals: 4-Benzylbenzenesulfonamide is commonly used in the synthesis of drugs, especially intermediates for protease inhibitors and anti-cancer drugs.
-Chemical research: The compound can also be used as an intermediate for chemical reagents and catalysts.
Method:
The preparation of 4-benzylbenzenesulfonamide is usually carried out by the following steps:
1. First, benzenesulfonyl chloride (C6H5SO2Cl) reacts with benzaldehyde (C6H5CH = O) to generate benzylsulfonamide (C6H5CH = NO2S).
2. Then, benzylbenzenesulfonamide is reacted with lithium aluminum hydride (LiAlH4) or a similar reducing agent to obtain 4-benzylbenzenesulfonamide.
Safety Information:
Please note the following safety precautions when using and storing 4-benzylbenzenesulfonamide:
-The compound is irritating and direct contact with skin and eyes should be avoided.
-When handling or handling 4-benzylbenzenesulfonamide, it is recommended to wear appropriate protective gloves, glasses and a mask.
-Avoid inhaling the dust or gas of the compound.
-Maintain well-ventilated laboratory conditions when using the compound.
-Store 4-benzylbenzenesulfonamide in a sealed container, away from fire and oxidizing agents.
Nature:
-Appearance: 4-Benzylbenzenesulfonamide is a white to slightly yellow crystalline powder.
-Melting point: Its melting point range is 121-123°C.
-Solubility: 4-benzyl benzene sulfonamide can be dissolved in most organic solvents, insoluble in water.
Use:
-Pharmaceuticals: 4-Benzylbenzenesulfonamide is commonly used in the synthesis of drugs, especially intermediates for protease inhibitors and anti-cancer drugs.
-Chemical research: The compound can also be used as an intermediate for chemical reagents and catalysts.
Method:
The preparation of 4-benzylbenzenesulfonamide is usually carried out by the following steps:
1. First, benzenesulfonyl chloride (C6H5SO2Cl) reacts with benzaldehyde (C6H5CH = O) to generate benzylsulfonamide (C6H5CH = NO2S).
2. Then, benzylbenzenesulfonamide is reacted with lithium aluminum hydride (LiAlH4) or a similar reducing agent to obtain 4-benzylbenzenesulfonamide.
Safety Information:
Please note the following safety precautions when using and storing 4-benzylbenzenesulfonamide:
-The compound is irritating and direct contact with skin and eyes should be avoided.
-When handling or handling 4-benzylbenzenesulfonamide, it is recommended to wear appropriate protective gloves, glasses and a mask.
-Avoid inhaling the dust or gas of the compound.
-Maintain well-ventilated laboratory conditions when using the compound.
-Store 4-benzylbenzenesulfonamide in a sealed container, away from fire and oxidizing agents.
Last Update：2024-04-09 21:01:54
