4-Bromo-2-(Trifluoromethyl)
4-bromo-2-(trifluoromethyl)pyridine
CAS: 887583-90-6
Molecular Formula: C6H3BrF3N
4-Bromo-2-(Trifluoromethyl) - Names and Identifiers
4-Bromo-2-(Trifluoromethyl) - Physico-chemical Properties
| Molecular Formula | C6H3BrF3N |
| Molar Mass | 225.99 |
| Density | 1.707±0.06 g/cm3(Predicted) |
| Boling Point | 167.4±35.0 °C(Predicted) |
| Flash Point | 55.042°C |
| Vapor Presure | 2.248mmHg at 25°C |
| pKa | -1.23±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.471 |
4-Bromo-2-(Trifluoromethyl) - Introduction
4-bromo-2-(trifluoromethyl)pyridine is an organic compound with the chemical formula C6H3BrF3N. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow crystal powder
-melting point: 46-50 ℃
-Boiling point: 164-166 ℃
-Density: 1.87g/cm³
-Solubility: Soluble in common organic solvents
Use:
- 4-bromo-2-(trifluoromethyl)pyridine is an important organic synthesis intermediate for the synthesis of other compounds, such as pharmaceutically active molecules, pesticides and insecticides.
-It can also be used as a catalyst, pigment and luminescent material research field.
Preparation Method:
- 4-bromo-2-(trifluoromethyl)pyridine can be synthesized by a variety of methods, among which commonly used methods include fluorination reaction and bromination reaction.
-Fluorination reaction: 4-bromopyridine can be reacted with a trifluoromethyl compound to obtain 4-bromo-2-(trifluoromethyl)pyridine.
-Bromination reaction: The target compound can be obtained by reacting 2-trifluoromethyl-4-chloropyridine with bromine.
Safety Information:
- 4-bromo-2-(trifluoromethyl)pyridine are generally considered to be relatively safe under routine use. However, due to its chemical activity, it is still necessary to follow appropriate safety procedures.
-Personal protective equipment such as goggles, chemical protective clothing and gloves should be worn during operation.
-Avoid inhalation, contact with skin and eyes. If exposed, rinse immediately with plenty of water and seek medical assistance.
-The substance should be stored in a cool, dry and well-ventilated place, away from fire and oxidizing agents.
Nature:
-Appearance: Colorless or light yellow crystal powder
-melting point: 46-50 ℃
-Boiling point: 164-166 ℃
-Density: 1.87g/cm³
-Solubility: Soluble in common organic solvents
Use:
- 4-bromo-2-(trifluoromethyl)pyridine is an important organic synthesis intermediate for the synthesis of other compounds, such as pharmaceutically active molecules, pesticides and insecticides.
-It can also be used as a catalyst, pigment and luminescent material research field.
Preparation Method:
- 4-bromo-2-(trifluoromethyl)pyridine can be synthesized by a variety of methods, among which commonly used methods include fluorination reaction and bromination reaction.
-Fluorination reaction: 4-bromopyridine can be reacted with a trifluoromethyl compound to obtain 4-bromo-2-(trifluoromethyl)pyridine.
-Bromination reaction: The target compound can be obtained by reacting 2-trifluoromethyl-4-chloropyridine with bromine.
Safety Information:
- 4-bromo-2-(trifluoromethyl)pyridine are generally considered to be relatively safe under routine use. However, due to its chemical activity, it is still necessary to follow appropriate safety procedures.
-Personal protective equipment such as goggles, chemical protective clothing and gloves should be worn during operation.
-Avoid inhalation, contact with skin and eyes. If exposed, rinse immediately with plenty of water and seek medical assistance.
-The substance should be stored in a cool, dry and well-ventilated place, away from fire and oxidizing agents.
Last Update：2024-04-09 21:04:16
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