4-Iodo-1H-indazol-3-amine
4-Iodo-1H-indazol-3-amine
CAS: 599191-73-8
Molecular Formula: C7H6IN3
4-Iodo-1H-indazol-3-amine - Names and Identifiers
| Name | 4-Iodo-1H-indazol-3-amine |
| Synonyms | 3-Amino-4-iodoindazole 4-Iodo-1H-indazol-3-amine 4-iodo-1H-indazol-3-amine 3-Amino-4-iodo-1H-indazole 1H-Indazol-3-aMine, 4-iodo- 4-Iodo-1H-indazol-3-ylamine 1H-Indazol-3-amine, 4-iodo- 3-Amino-4-iodo-1H-indazol... |
| CAS | 599191-73-8 |
| InChI | InChI=1/C7H6IN3/c8-4-2-1-3-5-6(4)7(9)11-10-5/h1-3H,(H3,9,10,11) |
4-Iodo-1H-indazol-3-amine - Physico-chemical Properties
| Molecular Formula | C7H6IN3 |
| Molar Mass | 259.05 |
| Density | 2.168±0.06 g/cm3(Predicted) |
| Melting Point | 154-155° |
| Boling Point | 452.2±25.0 °C(Predicted) |
| Flash Point | 227.262°C |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Solid |
| Color | Off-white to brown |
| pKa | 13.85±0.40(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.859 |
4-Iodo-1H-indazol-3-amine - Risk and Safety
| HS Code | 29339980 |
| Hazard Class | IRRITANT |
4-Iodo-1H-indazol-3-amine - Introduction
4-Iodo-1H-indazol-3-amine(4-Iodo-1H-indazol-3-amine) is an indazole compound having an iodine atom and an amino group.
Properties of the compound include:
-Appearance: White to yellow solid
-Molecular formula: C8H6IN3
-Molecular weight: 287.05g/mol
-melting point: 132-136 ℃
-Boiling point: 439.5 ℃
-Low solubility in water
4-Iodo-1H-indazol-3-amine has some applications in chemical research:
-It can be used as an intermediate in organic synthesis and can be used to synthesize other organic compounds with indazole skeleton.
-It has an indazole structure, may have certain biological activity, and can be used as a potential drug candidate compound in drug research.
The method of preparing 4-Iodo-1H-indazol-3-amine can be through the following steps:
1. The 3-indolone is converted to 3-bromo-indole (3-bromo-indazole) by an appropriate reaction.
2. 3-Bromo-indole reacts with sodium iodide (NaI) to generate 3-iodo-indole (3-iodo-indazole).
3. 3-iodo-indole is reacted with ammonia (NH3) to produce 4-Iodo-1H-indazol-3-amine.
As for the safety information of this compound, there is no detailed laboratory safety assessment data for reference. When handling the compound, strictly follow the safety procedures of the relevant chemical laboratory, wear appropriate personal protective equipment (such as laboratory gloves, goggles, etc.), and avoid inhalation, contact or ingestion. It is recommended that a reasonable evaluation and laboratory normative evaluation be carried out before the experiment. Consult or seek professional advice and guidance if necessary.
Properties of the compound include:
-Appearance: White to yellow solid
-Molecular formula: C8H6IN3
-Molecular weight: 287.05g/mol
-melting point: 132-136 ℃
-Boiling point: 439.5 ℃
-Low solubility in water
4-Iodo-1H-indazol-3-amine has some applications in chemical research:
-It can be used as an intermediate in organic synthesis and can be used to synthesize other organic compounds with indazole skeleton.
-It has an indazole structure, may have certain biological activity, and can be used as a potential drug candidate compound in drug research.
The method of preparing 4-Iodo-1H-indazol-3-amine can be through the following steps:
1. The 3-indolone is converted to 3-bromo-indole (3-bromo-indazole) by an appropriate reaction.
2. 3-Bromo-indole reacts with sodium iodide (NaI) to generate 3-iodo-indole (3-iodo-indazole).
3. 3-iodo-indole is reacted with ammonia (NH3) to produce 4-Iodo-1H-indazol-3-amine.
As for the safety information of this compound, there is no detailed laboratory safety assessment data for reference. When handling the compound, strictly follow the safety procedures of the relevant chemical laboratory, wear appropriate personal protective equipment (such as laboratory gloves, goggles, etc.), and avoid inhalation, contact or ingestion. It is recommended that a reasonable evaluation and laboratory normative evaluation be carried out before the experiment. Consult or seek professional advice and guidance if necessary.
Last Update：2024-04-09 21:54:55
Supplier List
Featured ProductsSpot supply
Product Name: 4-Iodo-1H-Indazol-3-Ylamine Visit Supplier Webpage Request for quotationCAS: 599191-73-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-Iodo-1H-indazol-3-amine Request for quotationCAS: 599191-73-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-Iodo-1H-Indazol-3-Ylamine Visit Supplier Webpage Request for quotationCAS: 599191-73-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 4-Iodo-1H-Indazol-3-Ylamine Visit Supplier Webpage Request for quotation
CAS: 599191-73-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 599191-73-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: 4-Iodo-1H-Indazol-3-Ylamine Visit Supplier Webpage Request for quotationCAS: 599191-73-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-Iodo-1H-indazol-3-amine Request for quotationCAS: 599191-73-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-Iodo-1H-Indazol-3-Ylamine Visit Supplier Webpage Request for quotationCAS: 599191-73-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 4-Iodo-1H-Indazol-3-Ylamine Visit Supplier Webpage Request for quotation
CAS: 599191-73-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 599191-73-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History