406482-19-7
(2-fluoro-5-methoxyphenyl)boronic acid
CAS: 406482-19-7
Molecular Formula: C7H8BFO3
406482-19-7 - Names and Identifiers
406482-19-7 - Physico-chemical Properties
| Molecular Formula | C7H8BFO3 |
| Molar Mass | 169.95 |
| Density | 1.26±0.1 g/cm3(Predicted) |
| Melting Point | 194-196 °C (lit.) |
| Boling Point | 333.1±52.0 °C(Predicted) |
| Flash Point | 155.2°C |
| Vapor Presure | 5.55E-05mmHg at 25°C |
| Appearance | Solid |
| Color | White to yellow |
| pKa | 7.90±0.58(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.503 |
| MDL | MFCD04974115 |
406482-19-7 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S28B - S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29319090 |
406482-19-7 - Introduction
(2-fluoro-5-methoxyphenyl)boronic acid is an organic compound with a chemical formula of C7H8BFO3 and a molecular weight of 169.95g/mol. Its nature is as follows:
1. appearance: white solid powder.
2. Melting point: about 160-163°C.
3. Solubility: Soluble in common organic solvents, such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), acetonitrile (ACN), etc.
(2-fluoro-5-methoxyphenyl) The main uses of boronic acid include:
1. organic synthesis: as a substrate and reagent in organic synthesis, it is commonly used in the group conversion reaction of phenylboronic acid, such as SuZ8 reaction, Suzuki reaction, etc. It can be used as an important intermediate for the synthesis of drugs, pesticides, natural products and functional materials.
2. chemical research: can be used as a ligand of organic synthesis catalyst.
The method for preparing (2-fluoro-5-methoxyphenyl)boronic acid generally includes the following steps:
1. First, 2-fluoro-5-methoxyphenol and tri-n-butyl borane are reacted under an inert atmosphere to obtain 2-fluoro-5-methoxyphenylborane.
2. Then, 2-fluoro-5-methoxybenzoborane is reacted with dilute sulfuric acid and boric acid to obtain (2-fluoro-5-methoxyphenyl)boronic acid.
Regarding its safety information, the following precautions should be followed:
1. May be irritating to eyes, skin and respiratory system, please use personal protective equipment, such as gloves and protective glasses.
2. Avoid inhalation or contact, and operate in a well-ventilated place.
3. Avoid contact with inflammables and oxidants to prevent fire and explosion.
4. should be stored away from high temperature and fire, keep the container sealed.
to sum up,(2-fluoro-5-methoxyphenyl)boronic acid has important application value in organic synthesis, and it is necessary to pay attention to safe use during experimental operation.
1. appearance: white solid powder.
2. Melting point: about 160-163°C.
3. Solubility: Soluble in common organic solvents, such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), acetonitrile (ACN), etc.
(2-fluoro-5-methoxyphenyl) The main uses of boronic acid include:
1. organic synthesis: as a substrate and reagent in organic synthesis, it is commonly used in the group conversion reaction of phenylboronic acid, such as SuZ8 reaction, Suzuki reaction, etc. It can be used as an important intermediate for the synthesis of drugs, pesticides, natural products and functional materials.
2. chemical research: can be used as a ligand of organic synthesis catalyst.
The method for preparing (2-fluoro-5-methoxyphenyl)boronic acid generally includes the following steps:
1. First, 2-fluoro-5-methoxyphenol and tri-n-butyl borane are reacted under an inert atmosphere to obtain 2-fluoro-5-methoxyphenylborane.
2. Then, 2-fluoro-5-methoxybenzoborane is reacted with dilute sulfuric acid and boric acid to obtain (2-fluoro-5-methoxyphenyl)boronic acid.
Regarding its safety information, the following precautions should be followed:
1. May be irritating to eyes, skin and respiratory system, please use personal protective equipment, such as gloves and protective glasses.
2. Avoid inhalation or contact, and operate in a well-ventilated place.
3. Avoid contact with inflammables and oxidants to prevent fire and explosion.
4. should be stored away from high temperature and fire, keep the container sealed.
to sum up,(2-fluoro-5-methoxyphenyl)boronic acid has important application value in organic synthesis, and it is necessary to pay attention to safe use during experimental operation.
Last Update：2024-04-09 21:54:55
Supplier List
Featured ProductsSpot supply
Product Name: 2-Fluoro-5-methoxyphenylboronic acid Visit Supplier Webpage Request for quotationCAS: 406482-19-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 2-Fluoro-5-methoxyphenylboronicacid Request for quotationCAS: 406482-19-7
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2-Fluoro-5-methoxyphenylboronic acid Visit Supplier Webpage Request for quotationCAS: 406482-19-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 2-Fluoro-5-methoxyphenylboronic acid Visit Supplier Webpage Request for quotation
CAS: 406482-19-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 406482-19-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: 2-Fluoro-5-methoxyphenylboronic acid Visit Supplier Webpage Request for quotationCAS: 406482-19-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 2-Fluoro-5-methoxyphenylboronicacid Request for quotationCAS: 406482-19-7
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2-Fluoro-5-methoxyphenylboronic acid Visit Supplier Webpage Request for quotationCAS: 406482-19-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 2-Fluoro-5-methoxyphenylboronic acid Visit Supplier Webpage Request for quotation
CAS: 406482-19-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 406482-19-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History