41088-89-5
Cbz-D-homoserine lactone
CAS: 41088-89-5
Molecular Formula: C12H13NO4
41088-89-5 - Names and Identifiers
41088-89-5 - Physico-chemical Properties
| Molecular Formula | C12H13NO4 |
| Molar Mass | 235.24 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| Melting Point | 126-128 °C |
| Boling Point | 466.1±44.0 °C(Predicted) |
| Appearance | White powder |
| pKa | 11.00±0.20(Predicted) |
| Storage Condition | 2-8°C |
41088-89-5 - Introduction
Cbz-D-homoserine lactone(Cbz-D-Constant acid lactone) is an organic compound with the following properties:
1. properties: Cbz-D-constant acid lactone is a white crystalline powder, with good solubility, soluble in ethanol, dimethylformamide (DMF) and dichloromethane and other organic solvents.
2. use: Cbz-D-constant acid lactone is often used as a reagent in organic synthesis, in the synthesis of drugs, peptides and proteins play an important role. It can be used to synthesize biologically active compounds such as antibiotics, prodrugs, and other natural products.
3. Preparation method: The preparation of Cbz-D-Constant acid lactone is usually carried out by the following steps:
-First, (D)-Constant amino acid is reacted with a chloroformylphenyl agent (such as Cbz-Cl) to obtain Cbz-D-Constant amino acid.
-Then, Cbz-D-constanoic acid is reacted with DALCl (dimethylaminomethylsilyl chloride) in tetrahydrofuran for lactonization to obtain Cbz-D-constanoic acid lactone.
4. Safety information: Due to the lack of specific laboratory conditions and operating details, the safety information of Cbz-D-Constant acid lactone cannot be evaluated in detail. However, all operations in the chemical laboratory should follow the correct safe operating procedures. When handling organic compounds, appropriate protective measures, such as wearing gloves, goggles and laboratory coats, should be taken to reduce contact with skin and eyes, and to avoid inhaling dust or gases from the compound. In addition, it should be operated in a well-ventilated area. If you intend to use or handle this compound, it is recommended to consult the relevant safety literature and chemical safety data forms.
1. properties: Cbz-D-constant acid lactone is a white crystalline powder, with good solubility, soluble in ethanol, dimethylformamide (DMF) and dichloromethane and other organic solvents.
2. use: Cbz-D-constant acid lactone is often used as a reagent in organic synthesis, in the synthesis of drugs, peptides and proteins play an important role. It can be used to synthesize biologically active compounds such as antibiotics, prodrugs, and other natural products.
3. Preparation method: The preparation of Cbz-D-Constant acid lactone is usually carried out by the following steps:
-First, (D)-Constant amino acid is reacted with a chloroformylphenyl agent (such as Cbz-Cl) to obtain Cbz-D-Constant amino acid.
-Then, Cbz-D-constanoic acid is reacted with DALCl (dimethylaminomethylsilyl chloride) in tetrahydrofuran for lactonization to obtain Cbz-D-constanoic acid lactone.
4. Safety information: Due to the lack of specific laboratory conditions and operating details, the safety information of Cbz-D-Constant acid lactone cannot be evaluated in detail. However, all operations in the chemical laboratory should follow the correct safe operating procedures. When handling organic compounds, appropriate protective measures, such as wearing gloves, goggles and laboratory coats, should be taken to reduce contact with skin and eyes, and to avoid inhaling dust or gases from the compound. In addition, it should be operated in a well-ventilated area. If you intend to use or handle this compound, it is recommended to consult the relevant safety literature and chemical safety data forms.
Last Update：2024-04-09 21:01:54
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