41753-55-3
Ophiopogonin D
CAS: 41753-55-3
Molecular Formula: C44H70O16
41753-55-3 - Names and Identifiers
41753-55-3 - Physico-chemical Properties
| Molecular Formula | C44H70O16 |
| Molar Mass | 855.021 |
| Melting Point | 263-265°C |
| Specific Rotation(α) | (c, 0.66 in Py)-107.9 |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | White powder |
| Storage Condition | 2-8℃ |
| Sensitive | Easily absorbing moisture |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Ophiopogon japonicus Ophiopogon japonicus ( L .f.)KerGawl.. |
41753-55-3 - Reference
| Reference Show more | 1. Miao Ju Lian Huang Zhao-Chang Wang Cheng-jun, etc. Determination of ophiopogonin D in shengmai decoction by HPLC-ELSD [J]. Chinese patent medicine, 2015, 37(002): -464. 2. He Li, Jin Hong, Liang, Xuelan et al. Determination of Ophiopogon japonicus saponin D in Root and fibrous roots of Ophiopogon japonicus by HPLC [J]. West China Journal of Pharmacy 2014(5):583-584. 3. Xu Xiaofang, Chen Wenting, Liu Min, etc. Study on the quality standard of compound aconite oral liquid [J]. Chinese traditional medicines, 2016, 38(004):815-819. 4. Jin Hong, Wang hdong, He Li, et al. Comparative study on histology and saponin content of Ophiopogon japonicus and its fibrous roots in Sichuan [J]. Chinese Herbal Medicine, 2014, 45(7):1002-1005. 5. Meng Chen, Yuan Cai Hua, Zhang Chen, etc. Ophiopogonin-D protects against adriamycin-induced myocardial injury by alleviating endoplasmic reticulum stress [J]. Chinese Journal of Pharmacy, 2014(8):1117-1123. 6. Yu Jian, Xu Xiaozhen, Gu Liqiang, etc. Simultaneous determination of nine saponins in Shenmai injection by high performance liquid chromatography-tandem mass spectrometry [J]. Chinese Journal of Traditional Chinese Medicine, 2014. 7. Wu, Lingna, et al. "Interactions of the major effective components in Shengmai formula with breast cancer resistance protein at the cellular and vesicular levels." Biomedicine & Pharmacotherapy 133 (2021): 110939.https://doi.org/10.1016/j.biopha.2020.11093 8. Huang X, Wang Y, Wang Y, Yang L, Wang J, Gao Y: Ophiopogonin D Reduces Myocardial Ischemia-Reperfusion Injury via Upregulating CYP2J3/EETs in Rats. Cell Physiol Biochem 2018;49:1646-1658. doi: 10.1159/000493500 9. [IF=0] Xiaoyan Huang et al."Ophiopogonin D Reduces Myocardial Ischemia-Reperfusion Injury via Upregulating CYP2J3/EETs in Rats."Cell Physiol Biochem. 2018;49(4):1646-1658 10. [IF=5.34] Tao Zhan et al."The major effective components in Shengmai Formula interact with sodium taurocholate co-transporting polypeptide."Phytomedicine. 2019 Jun;59:152916 11. [IF=5.34] You-Ping Wu et al."Evidences for the mechanism of Shenmai injection antagonizing doxorubicin-induced cardiotoxicity."Phytomedicine. 2021 Jul;88:153597 12. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150 13. [IF=4.207] Ziyu Cheng et al."Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis."J Cancer. 2022; 13(2): 715-727 |
41753-55-3 - Introduction
Ophiopogonin D is a natural product, mainly found in the traditional Chinese medicine Ophiopogonin. It is a kind of saponins, chemical structure is mainly composed of terpenoid part and carbohydrate part.
opiopogonin D has a variety of biological activities, including antioxidant, anti-inflammatory, anti-tumor and so on. Studies have shown that it has the effect of improving immune function, anti-fatigue, protecting cardiovascular and cerebrovascular and anti-aging.
The preparation method of opiopogonin D is generally obtained by extraction, separation and purification. Commonly used methods include ultrasonic-assisted extraction, solvent reflux extraction, silica gel column chromatography, etc.
In terms of safety, Ophiopogonin D is a natural product and is generally considered to have good safety. But still need to pay attention to the following points: First, individual differences make some people may be sensitive to the substance, which may cause allergic reactions. Secondly, the recommend of dosage should be observed during use to avoid excessive use. Finally, for specific groups of people, such as pregnant women, lactating women and children, it should be used with caution and under the guidance of a doctor.
In conclusion, Ophiopogonin D has a variety of biological activities and is widely used in the field of traditional Chinese medicine. However, it is necessary to pay attention to safety issues during use and ensure that it is used under the guidance of a doctor.
opiopogonin D has a variety of biological activities, including antioxidant, anti-inflammatory, anti-tumor and so on. Studies have shown that it has the effect of improving immune function, anti-fatigue, protecting cardiovascular and cerebrovascular and anti-aging.
The preparation method of opiopogonin D is generally obtained by extraction, separation and purification. Commonly used methods include ultrasonic-assisted extraction, solvent reflux extraction, silica gel column chromatography, etc.
In terms of safety, Ophiopogonin D is a natural product and is generally considered to have good safety. But still need to pay attention to the following points: First, individual differences make some people may be sensitive to the substance, which may cause allergic reactions. Secondly, the recommend of dosage should be observed during use to avoid excessive use. Finally, for specific groups of people, such as pregnant women, lactating women and children, it should be used with caution and under the guidance of a doctor.
In conclusion, Ophiopogonin D has a variety of biological activities and is widely used in the field of traditional Chinese medicine. However, it is necessary to pay attention to safety issues during use and ensure that it is used under the guidance of a doctor.
Last Update：2024-04-09 21:31:56
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Mobile: +86-18621343501
QQ: 2881950922
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41753-55-3
103548-82-9
7-hydroxyquinoline-8-carbaldehyde
硫酸汞(II), ACS MIN
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103548-82-9
7-hydroxyquinoline-8-carbaldehyde
硫酸汞(II), ACS MIN
Demethyl
HEPE
溶剂黄21
Tin zinc oxide