42417-66-3
N-Cbz-N-methyl-L-isoleucine
CAS: 42417-66-3
Molecular Formula: C15H21NO4
42417-66-3 - Names and Identifiers
42417-66-3 - Physico-chemical Properties
| Molecular Formula | C15H21NO4 |
| Molar Mass | 279.33 |
| Appearance | Powder |
| Color | White to off-white |
| Storage Condition | Sealed in dry,Room Temperature |
42417-66-3 - Risk and Safety
| WGK Germany | 3 |
42417-66-3 - Introduction
N-Cbz-N-methyl-L-isoleucine(N-Cbz-N-methyl-L-isoleucine) is an amino acid derivative. Its chemical formula is C18H25NO4 and its molecular weight is 323.39g/mol. It is a white crystalline powder, soluble in organic solvents such as methanol and dichloromethane.
The main use of N-Cbz-N-methyl-L-isoleucine is as an intermediate in organic synthesis. It has important applications in drug synthesis and peptide synthesis. It can be introduced into the molecule as a protecting group or a group to protect a specific functional group in the amino acid or peptide chain, and the protecting group is removed after the end of the reaction.
The method of preparing N-Cbz-N-methyl-L-isoleucine is generally carried out by synthetic chemical methods. For example, a methyl group can be introduced by reacting a N-Cbz-L-isoleucine with a methylating agent, followed by removal of the protecting group (as exemplified by a hydroxylamine solution or a hydrogenating agent) to give the desired product.
Regarding safety information, N-Cbz-N-methyl-L-isoleucine relative toxicity data is relatively limited. In general, however, chemicals should follow appropriate laboratory practices and safe operating procedures. Care should be taken to avoid contact with skin, eyes and respiratory tract during operation. If contact occurs, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a cool, dry, well-ventilated place, away from fire and oxidizing agents. When handling or disposing of the compound, follow local regulations and regulations and take appropriate protective measures.
The main use of N-Cbz-N-methyl-L-isoleucine is as an intermediate in organic synthesis. It has important applications in drug synthesis and peptide synthesis. It can be introduced into the molecule as a protecting group or a group to protect a specific functional group in the amino acid or peptide chain, and the protecting group is removed after the end of the reaction.
The method of preparing N-Cbz-N-methyl-L-isoleucine is generally carried out by synthetic chemical methods. For example, a methyl group can be introduced by reacting a N-Cbz-L-isoleucine with a methylating agent, followed by removal of the protecting group (as exemplified by a hydroxylamine solution or a hydrogenating agent) to give the desired product.
Regarding safety information, N-Cbz-N-methyl-L-isoleucine relative toxicity data is relatively limited. In general, however, chemicals should follow appropriate laboratory practices and safe operating procedures. Care should be taken to avoid contact with skin, eyes and respiratory tract during operation. If contact occurs, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a cool, dry, well-ventilated place, away from fire and oxidizing agents. When handling or disposing of the compound, follow local regulations and regulations and take appropriate protective measures.
Last Update：2024-04-09 20:52:54
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CAS: 42417-66-3
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