4353-32-6
H-Arg(Tos)-OH
CAS: 4353-32-6
Molecular Formula: C13H20N4O4S
4353-32-6 - Names and Identifiers
| Name | H-Arg(Tos)-OH |
| Synonyms | H-Arg(Tos)-OH H-Arg (Tos)-OH H-D-ARG(TOS)-OH H-D-Arg(Tos)-OH N-g-(Tos)-L-Arg D-ARGININE(TOS)-OH NG-TOSYL-D-ARGININE N'-p-Tosyl-L-arginine N-OMEGA-TOSYL-D-ARGININE NALPHA-(4-TOLUENESULFONYL)-L-ARGININE N-OMEGA-(4-TOLUENESULFONYL)-D-ARGININE |
| CAS | 4353-32-6 |
| InChI | InChI=1/C13H20N4O4S/c1-9-4-6-10(7-5-9)22(20,21)17-13(15)16-8-2-3-11(14)12(18)19/h4-7,11H,2-3,8,14H2,1H3,(H,18,19)(H3,15,16,17)/t11-/m0/s1 |
4353-32-6 - Physico-chemical Properties
| Molecular Formula | C13H20N4O4S |
| Molar Mass | 328.39 |
| Density | 1.42±0.1 g/cm3(Predicted) |
| Melting Point | 146-150 °C |
| Boling Point | 528.3±60.0 °C(Predicted) |
| Flash Point | 290.9°C |
| Vapor Presure | 2.95E-13mmHg at 25°C |
| pKa | 2.46±0.24(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.621 |
4353-32-6 - Introduction
H-Arg(Tos)-OH(H-Arg(Tos)-OH) is an organic compound whose chemical formula is C18H22N4O5S.
H-Arg(Tos)-OH has the following properties:
-Appearance: White crystalline powder.
-Solubility: It can be dissolved in water, and part of it can be dissolved in ethanol or dimethyl sulfoxide.
-Stability: Very stable in a dry environment. However, in a high humidity environment, it may absorb moisture, so it should be stored in a sealed container.
The main uses of H-Arg(Tos)-OH include:
-Biochemical research: as a starting material for the synthesis of peptides and proteins.
-Drug development: commonly used in the synthesis of antibiotics, anti-tumor drugs.
-Biotechnology applications: for the synthesis of molecular probes, fluorescent dyes, protein modification, etc.
The general method for preparing H-Arg(Tos)-OH is as follows:
1. p-toluenesulfonyl chloride (tosyl chloride) was first prepared. The reaction of p-toluenesulfonic acid (p-toluenesulfonic acid) with a certain proportion of thionyl chloride (thionyl chloride) produces p-toluenesulfonyl chloride.
2. React with L-arginine. Acylation of p-toluenesulfonyl chloride with L-arginine produces H-Arg(Tos)-OH.
in the operation should pay attention to safety matters:
-Wear protective clothing, goggles and gloves.
-Operate in a well-ventilated laboratory to avoid contact with skin and inhalation of gases.
-When handling the compound, avoid reaction with acids or oxidizing agents.
-Try to avoid discharging the compound into water or the environment, and follow local regulations for disposal.
The above provides some basic information about H-Arg(Tos)-OH. The specific operation also needs to be studied and operated in detail according to the actual situation.
H-Arg(Tos)-OH has the following properties:
-Appearance: White crystalline powder.
-Solubility: It can be dissolved in water, and part of it can be dissolved in ethanol or dimethyl sulfoxide.
-Stability: Very stable in a dry environment. However, in a high humidity environment, it may absorb moisture, so it should be stored in a sealed container.
The main uses of H-Arg(Tos)-OH include:
-Biochemical research: as a starting material for the synthesis of peptides and proteins.
-Drug development: commonly used in the synthesis of antibiotics, anti-tumor drugs.
-Biotechnology applications: for the synthesis of molecular probes, fluorescent dyes, protein modification, etc.
The general method for preparing H-Arg(Tos)-OH is as follows:
1. p-toluenesulfonyl chloride (tosyl chloride) was first prepared. The reaction of p-toluenesulfonic acid (p-toluenesulfonic acid) with a certain proportion of thionyl chloride (thionyl chloride) produces p-toluenesulfonyl chloride.
2. React with L-arginine. Acylation of p-toluenesulfonyl chloride with L-arginine produces H-Arg(Tos)-OH.
in the operation should pay attention to safety matters:
-Wear protective clothing, goggles and gloves.
-Operate in a well-ventilated laboratory to avoid contact with skin and inhalation of gases.
-When handling the compound, avoid reaction with acids or oxidizing agents.
-Try to avoid discharging the compound into water or the environment, and follow local regulations for disposal.
The above provides some basic information about H-Arg(Tos)-OH. The specific operation also needs to be studied and operated in detail according to the actual situation.
Last Update：2024-04-09 20:49:11
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