448947-81-7
GlyT2-IN-1
CAS: 448947-81-7
Molecular Formula: C13H8Cl2N4S2
448947-81-7 - Names and Identifiers
448947-81-7 - Physico-chemical Properties
| Molecular Formula | C13H8Cl2N4S2 |
| Molar Mass | 355.27 |
| Density | 1.58±0.1 g/cm3(Predicted) |
| Melting Point | 136 - 138°C |
| Boling Point | 538.4±60.0 °C(Predicted) |
| Solubility | DMSO: ≥ 34 mg/mL |
| Appearance | powder |
| Color | white to beige |
| pKa | -1.32±0.10(Predicted) |
| Storage Condition | 2-8°C |
448947-81-7 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.815 ml | 14.074 ml | 28.148 ml |
| 5 mM | 0.563 ml | 2.815 ml | 5.63 ml |
| 10 mM | 0.281 ml | 1.407 ml | 2.815 ml |
| 5 mM | 0.056 ml | 0.281 ml | 0.563 ml |
Last Update：2024-01-02 23:10:35
448947-81-7 - Reference Information
| biological activity | Yoda1 is an agonist of human and mouse-derived Piezo1. The mouse-derived EC50 is 17.1 μM and the human-derived EC50 is 26.6 μM. In the absence of other cellular components, Yoda 1 activates purified Piezo 1 channels. |
| target | TargetValue mPiezo1 (Cell-free say) 17.1 μM(EC50) hPiezo1 (Cell-free say) 26.6 μM(EC50) |
| Target | Value |
| mPiezo1 (Cell-free assay) | 17.1 μM(EC50) |
| hPiezo1 (Cell-free assay) | 26.6 μM(EC50) |
Last Update：2024-04-09 21:54:55
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