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475231-21-1

3'-Hydroxypterostilbene

CAS: 475231-21-1

Molecular Formula: C16H16O4

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475231-21-1 - Names and Identifiers

Name 3'-Hydroxypterostilbene
Synonyms 3'-Hydroxypterostilbene
3'-H518-82-1ydroxypterostilbene
4-[2-(3,5-dimethoxyphenyl)ethenyl]benzene-1,2-diol
4-(2-(3,5-dimethoxyphenyl)ethenyl)-1,2-benzenediol
4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]benzene-1,2-diol
4-[(1E)-2-(3,5-Dimethoxyphenyl)vinyl]benzene-1,2-diol
4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]benzene-1,2-diol
4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]benzene-1,2-diol
1,2-benzenediol, 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-
1,2-Benzenediol,4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-
CAS 475231-21-1
EINECS 610-361-1
InChI InChI=1/C16H16O4/c1-19-13-7-12(8-14(10-13)20-2)4-3-11-5-6-15(17)16(18)9-11/h3-10,17-18H,1-2H3/b4-3+

475231-21-1 - Physico-chemical Properties

Molecular FormulaC16H16O4
Molar Mass272.3
Density1.252g/cm3
Melting Point112-115 °C
Boling Point469.67°C at 760 mmHg
Flash Point237.848°C
Solubility DMSO : 260 mg/mL (954.83 mM; Need ultrasonic)
Vapor Presure0mmHg at 25°C
AppearanceWhite-like crystalline powder
Storage Condition2-8°C
Refractive Index1.665
MDLMFCD12407156

475231-21-1 - Reference Information

biological activity 3 '-Hydroxypterostilbene (3'-HPT) is one of the active ingredients in the hearts of swalk bean and rosewood, which may be effective in treating different types of malignant hematological tumors. 3 '-Hydroxypterostilbene can effectively inhibit the growth of human colon cancer cells by inducing apoptosis and autophagy. The IC50 values for COLO 205,HCT-116 and HT-29 cells are 9.0 µM, 40.2 µM and 70.9 µM respectively. The 3 '-Hydroxypterostilbene inhibits p70S6K and p38MAPK signaling pathways in the PI3K/Akt/mTOR signaling pathway and activates the ERK1/2, JNK1/2 signaling pathways.
target TargetValue p70S6K () p38MAPK ()
TargetValue
Last Update:2024-04-09 21:11:58
475231-21-1
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475231-21-1
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