5-Bromo-2-Chlorobenzaldehyde
5-Bromo-2-Chlorobenzaldehyde
CAS: 189628-37-3
Molecular Formula: C7H4BrClO
5-Bromo-2-Chlorobenzaldehyde - Names and Identifiers
| Name | 5-Bromo-2-Chlorobenzaldehyde |
| Synonyms | 2-chloro-5-bromobenzaldehyde 5-Bromo-2-Chlorobenzaldehyde Benzaldehyde, 5-broMo-2-chloro- 5-BROMO-2-CHLOROBENZALDEHYDE fandachem |
| CAS | 189628-37-3 |
| InChI | InChI=1/C7H4BrClO/c8-6-1-2-7(9)5(3-6)4-10/h1-4H |
5-Bromo-2-Chlorobenzaldehyde - Physico-chemical Properties
| Molecular Formula | C7H4BrClO |
| Molar Mass | 219.46 |
| Density | 1.698 |
| Melting Point | 43-46℃ |
| Boling Point | 261℃ |
| Flash Point | 112℃ |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.012mmHg at 25°C |
| Appearance | Solid |
| Color | Off-white to pale yellow |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.623 |
5-Bromo-2-Chlorobenzaldehyde - Reference Information
| use | 5-bromo-2-chlorobenzaldehyde is an important pharmaceutical and chemical raw material, which can be used to synthesize multiple drugs for treating diabetes, such as Dapagliflozin, Ertugliflozin, Empagliflozin, etc. |
| Preparation method | Using 5-bromo-2-chlorobenzene methanol as raw material, it is produced by oxidation in Pyridinium Chlorochromate)/CH2Cl mixed solvent. In the patent document W02004074270, PDC (pyridinium dichromate, Pyridinium dichromate) /CH2Cl is used to oxidize 5-bromo-2-chlorobenzyl methanol, and then to obtain 5-bromo-2-chlorobenzaldehyde by oxidation. |
Last Update：2024-04-09 02:00:07
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