5-Bromo-2-Ethynylpyridine
5-Bromo-2-Ethynylpyridine
CAS: 111770-86-6
Molecular Formula: C7H4BrN
5-Bromo-2-Ethynylpyridine - Names and Identifiers
| Name | 5-Bromo-2-Ethynylpyridine |
| Synonyms | 5-BROMO-2-ETHYNYLPYRIDINE 2-Ethynyl-5-bromopyridine 5-Bromo-2-Ethynylpyridine Pyridine,5-bromo-2-ethynyl- |
| CAS | 111770-86-6 |
| InChI | InChI=1/C7H4BrN/c1-2-7-4-3-6(8)5-9-7/h1,3-5H |
5-Bromo-2-Ethynylpyridine - Physico-chemical Properties
| Molecular Formula | C7H4BrN |
| Molar Mass | 182.02 |
| Density | 1.60 |
| Melting Point | 84-86℃ |
| Boling Point | 212℃ |
| Flash Point | 82℃ |
| Vapor Presure | 0.256mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Light yellow to Light orange |
| pKa | -0.09±0.22(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.609 |
5-Bromo-2-Ethynylpyridine - Introduction
5-Bromo-2-acetylene pyridine is an organic compound with the chemical formula C9H6BrN. The following is a description of its nature, use, formulation and safety information:
Nature:
1. Appearance: 5-bromo -2-acetylene pyridine is a white crystalline solid.
2. Melting point: The melting point of the compound is about 105-109 degrees Celsius.
3. Solubility: 5-bromo -2-acetylene pyridine is soluble in common organic solvents, such as ethanol, chloroform and dimethyl sulfoxide.
Use:
1. 5-Bromo-2-acetylene pyridine is commonly used as an intermediate in organic synthesis and is used in the synthesis of other organic compounds.
2. It can also be used in the preparation of organic optoelectronic devices, such as organic light-emitting diodes (OLED).
Preparation Method:
There are many preparation methods of 5-bromo -2-acetylene pyridine, and a common method is obtained by bromination of bromo-ethynyl phenol. The specific step is to react bromo-p-ethynylphenol with dimethyl dicarbonate to generate bromo-p-ethynylphenol dimethyl ester. The bromo-p-ethynylphenol dimethyl ester is then reacted with pyrrole in the presence of a base to yield 5-bromo-2-acetynylpyridine.
Safety Information:
1. 5-Bromo -2-acetylene pyridine is irritating, please avoid direct contact with skin, eyes and respiratory tract. Appropriate protective equipment such as gloves, glasses and breathing masks should be worn during operation.
2. When using, storing, and handling this compound, follow chemical safety practices and comply with all applicable safety regulations.
3. 5-Bromo -2-acetylene pyridine should be stored in a dry, cool, well-ventilated place, and away from fire and flammable materials.
4. When abandoning, please dispose of it in accordance with local regulations to ensure that the environment is not polluted.
Nature:
1. Appearance: 5-bromo -2-acetylene pyridine is a white crystalline solid.
2. Melting point: The melting point of the compound is about 105-109 degrees Celsius.
3. Solubility: 5-bromo -2-acetylene pyridine is soluble in common organic solvents, such as ethanol, chloroform and dimethyl sulfoxide.
Use:
1. 5-Bromo-2-acetylene pyridine is commonly used as an intermediate in organic synthesis and is used in the synthesis of other organic compounds.
2. It can also be used in the preparation of organic optoelectronic devices, such as organic light-emitting diodes (OLED).
Preparation Method:
There are many preparation methods of 5-bromo -2-acetylene pyridine, and a common method is obtained by bromination of bromo-ethynyl phenol. The specific step is to react bromo-p-ethynylphenol with dimethyl dicarbonate to generate bromo-p-ethynylphenol dimethyl ester. The bromo-p-ethynylphenol dimethyl ester is then reacted with pyrrole in the presence of a base to yield 5-bromo-2-acetynylpyridine.
Safety Information:
1. 5-Bromo -2-acetylene pyridine is irritating, please avoid direct contact with skin, eyes and respiratory tract. Appropriate protective equipment such as gloves, glasses and breathing masks should be worn during operation.
2. When using, storing, and handling this compound, follow chemical safety practices and comply with all applicable safety regulations.
3. 5-Bromo -2-acetylene pyridine should be stored in a dry, cool, well-ventilated place, and away from fire and flammable materials.
4. When abandoning, please dispose of it in accordance with local regulations to ensure that the environment is not polluted.
Last Update：2024-04-10 22:29:15
Supplier List
Featured ProductsSpot supply
Product Name: 5-Bromo-2-ethynylpyridine Visit Supplier Webpage Request for quotationCAS: 111770-86-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 5-Bromo-2-ethynylpyridine Request for quotationCAS: 111770-86-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 5-Bromo-2-ethynylpyridine Visit Supplier Webpage Request for quotationCAS: 111770-86-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 5-BROMO-2-ETHYNYLPYRIDINE Visit Supplier Webpage Request for quotationCAS: 111770-86-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 5-BROMO-2-ETHYNYLPYRIDINE Visit Supplier Webpage Request for quotation
CAS: 111770-86-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 111770-86-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: 5-Bromo-2-ethynylpyridine Visit Supplier Webpage Request for quotationCAS: 111770-86-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 5-Bromo-2-ethynylpyridine Request for quotationCAS: 111770-86-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 5-Bromo-2-ethynylpyridine Visit Supplier Webpage Request for quotationCAS: 111770-86-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 5-BROMO-2-ETHYNYLPYRIDINE Visit Supplier Webpage Request for quotationCAS: 111770-86-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 5-BROMO-2-ETHYNYLPYRIDINE Visit Supplier Webpage Request for quotation
CAS: 111770-86-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 111770-86-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History