5-Formylthiazole
Thiazole-5-carboxaldehyde
CAS: 1003-32-3
Molecular Formula: C4H3NOS
5-Formylthiazole - Names and Identifiers
| Name | Thiazole-5-carboxaldehyde |
| Synonyms | 5-Formylthiazole 5-THIAOLECARBOXALDEHYDE THIAZOLE-5-CARBALDEHYDE 5-Thiazolecarboxaldehyde 5-THIAZOLECARBOXALDEHYDE THIAZOLE-5-CARBOXALDEHYDE Thiazole-5-carboxaldehyde Thiazole-5-carboxyaldehyde Thiazole-5-carboxaldehyde 1,3-Thiazole-5-carboxaldehyde |
| CAS | 1003-32-3 |
| InChI | InChI=1/C4H3NOS/c6-2-4-1-5-3-7-4/h1-3H |
| InChIKey | ZXRLWHGLEJGMNO-UHFFFAOYSA-N |
5-Formylthiazole - Physico-chemical Properties
| Molecular Formula | C4H3NOS |
| Molar Mass | 113.14 |
| Density | 1.304 g/mL at 25 °C |
| Melting Point | 229 °C (decomp) |
| Boling Point | 92-94 °C/16 mmHg |
| Flash Point | 98 °C |
| Vapor Presure | 0.102mmHg at 25°C |
| Appearance | Solid |
| Color | White or Colorless to Yellow |
| pKa | 0.94±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Sensitive to air |
| Refractive Index | 1.5874 |
| MDL | MFCD02179516 |
5-Formylthiazole - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact R36 - Irritating to the eyes R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| HS Code | 29341000 |
| Hazard Class | IRRITANT |
5-Formylthiazole - Introduction
5-thiazolecarboxaldehyde is an organic compound with the chemical formula C4H3NOS. The following is an introduction to the properties, uses, preparation methods and safety information of 5-thiazole formaldehyde:
Nature:
-Appearance is colorless or light yellow solid;
-flammable, soluble in some solvents, such as alcohol and ether;
-has a special sulfide odor;
-Decomposition at high temperature.
Use:
-5-thiazolecarboxaldehyde is widely used in organic synthesis and can be used as an intermediate or raw material for chemical reactions;
-It is used as a key intermediate for the synthesis of a variety of drugs in the pharmaceutical field, such as certain antibiotics and anti-cancer drugs.
Preparation Method:
-The synthesis of 5-thiazolecarboxaldehyde is generally achieved by the conversion of the thiazole ring. Common methods include the reaction of thiazole with formaldehyde, and the reaction of thiazole thiol with formaldehyde.
Safety Information:
-5-thiazolecarboxaldehyde is an irritant substance that may cause irritation in contact with skin and eyes;
-Wear protective gloves, goggles and protective clothing during use and handling;
-Avoid inhaling its vapor or dust, and need to operate in a well-ventilated place;
-When storing, it should be sealed and stored in a cool, dry place, away from heat and fire.
Nature:
-Appearance is colorless or light yellow solid;
-flammable, soluble in some solvents, such as alcohol and ether;
-has a special sulfide odor;
-Decomposition at high temperature.
Use:
-5-thiazolecarboxaldehyde is widely used in organic synthesis and can be used as an intermediate or raw material for chemical reactions;
-It is used as a key intermediate for the synthesis of a variety of drugs in the pharmaceutical field, such as certain antibiotics and anti-cancer drugs.
Preparation Method:
-The synthesis of 5-thiazolecarboxaldehyde is generally achieved by the conversion of the thiazole ring. Common methods include the reaction of thiazole with formaldehyde, and the reaction of thiazole thiol with formaldehyde.
Safety Information:
-5-thiazolecarboxaldehyde is an irritant substance that may cause irritation in contact with skin and eyes;
-Wear protective gloves, goggles and protective clothing during use and handling;
-Avoid inhaling its vapor or dust, and need to operate in a well-ventilated place;
-When storing, it should be sealed and stored in a cool, dry place, away from heat and fire.
Last Update：2024-04-09 02:00:40
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