521-32-4
8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
CAS: 521-32-4
Molecular Formula: C31H20O10
521-32-4 - Names and Identifiers
| Name | 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one |
| Synonyms | bilobetin BILOBETIN BILOBETIN(P)(PLEASE CALL) 4'-Monomethylamentoflavone AMENTOFLAVONE-4''-METHYL ETHER AMENTOFLAVONE-4'''-METHYL ETHER 4',5,5'',7,7''-Pentahydroxy-4'''-methoxy-8,3'''-biflavone 3''',8-Biflavone,4',5,5'',7,7''-pentahydroxy-4'''-methoxy- (7CI,8CI) 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one 5,7-Dihydroxy-8-[2-methoxy-5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenyl]-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 4H-1-benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)- |
| CAS | 521-32-4 |
| EINECS | 200-258-5 |
| InChI | InChI=1/C31H20O10/c1-39-24-7-4-15(26-12-22(37)29-19(34)9-17(33)10-27(29)40-26)8-18(24)28-20(35)11-21(36)30-23(38)13-25(41-31(28)30)14-2-5-16(32)6-3-14/h2-13,32-36H,1H3 |
521-32-4 - Physico-chemical Properties
| Molecular Formula | C31H20O10 |
| Molar Mass | 552.48 |
| Density | 1.576±0.06 g/cm3(Predicted) |
| Melting Point | 225 °C |
| Boling Point | 869.9±65.0 °C(Predicted) |
| Flash Point | 291.9°C |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Vapor Presure | 7.34E-32mmHg at 25°C |
| Appearance | Powder |
| pKa | 6.18±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.75 |
| MDL | MFCD00597036 |
| Physical and Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents, derived from Ginkgo biloba. |
521-32-4 - Reference
| Reference Show more | 1. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 |
521-32-4 - Introduction
8-[5-(5,)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, also known as ginkgo flavone, it is a natural compound extracted from the seeds of ginkgo. It has the following properties:
1. Appearance: 8-[5-(5,)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one is a yellow crystalline powder.
2. Solubility: 8-[5-(5, Ti)-2-methoxyphenyl]-5,7-dihydroxyxy-2-(4-hydroxyphenyl)-4H-chromen-4-one is soluble in organic solvents such as ethanol, dimethyl sulfoxide and dimethylformamide.
3. Stability: Under neutral and weakly acidic conditions, 8-[5-(5)-2-methoxyphenyl]-5,7-dihydxy-2-(4-hydroxyphenyl)-4H-chromen-4-one has good stability.
8-[5-(5, phenyl)-2-methoxyphenyl]-5,7-dihydy-2-(4-hydroxyphenyl)-4H-chromen-4-one has many uses:
1. Oxidation resistance: 8-[5-(5, phenyl)-2-methoxyphenyl]-5,7-dihydy-2-(4-hydroxyphenyl)-4H-chromen-4-one has significant antioxidant activity, which can scavenge free radicals and reduce oxidative damage.
2. Anti-inflammatory: Studies have shown that 8-[5-(5, 4-hydroxyphenyl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one has certain anti-inflammatory activity and can reduce inflammatory symptoms.
3. Antitumor activity: 8-[5-(5, phenyl)-2-methoxyphenyl]-5,7-dihydy-2-(4-hydroxyphenyl)-4H-chromen-4-one was found to have antitumor activity, it can inhibit the growth and spread of tumor cells.
The method of preparing 8-[5-(5, 4-hydroxyphenyl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one includes: first, the ginkgo seed powder is mixed with an appropriate amount of solvent (such as alcohol solvent) and stirred, and then the steps of extraction, concentration and crystallization are carried out.
For the current study, 8-[5-(5, phenyl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one is generally considered safe. However, as a compound, adverse reactions may occur if used in excess or for a long time. Before using 8-[5-(5,-2-methoxyphenyl]-5,7-dihydroxyxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, it is best to consult a doctor's advice, to understand the specific dosage and method of use.
1. Appearance: 8-[5-(5,)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one is a yellow crystalline powder.
2. Solubility: 8-[5-(5, Ti)-2-methoxyphenyl]-5,7-dihydroxyxy-2-(4-hydroxyphenyl)-4H-chromen-4-one is soluble in organic solvents such as ethanol, dimethyl sulfoxide and dimethylformamide.
3. Stability: Under neutral and weakly acidic conditions, 8-[5-(5)-2-methoxyphenyl]-5,7-dihydxy-2-(4-hydroxyphenyl)-4H-chromen-4-one has good stability.
8-[5-(5, phenyl)-2-methoxyphenyl]-5,7-dihydy-2-(4-hydroxyphenyl)-4H-chromen-4-one has many uses:
1. Oxidation resistance: 8-[5-(5, phenyl)-2-methoxyphenyl]-5,7-dihydy-2-(4-hydroxyphenyl)-4H-chromen-4-one has significant antioxidant activity, which can scavenge free radicals and reduce oxidative damage.
2. Anti-inflammatory: Studies have shown that 8-[5-(5, 4-hydroxyphenyl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one has certain anti-inflammatory activity and can reduce inflammatory symptoms.
3. Antitumor activity: 8-[5-(5, phenyl)-2-methoxyphenyl]-5,7-dihydy-2-(4-hydroxyphenyl)-4H-chromen-4-one was found to have antitumor activity, it can inhibit the growth and spread of tumor cells.
The method of preparing 8-[5-(5, 4-hydroxyphenyl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one includes: first, the ginkgo seed powder is mixed with an appropriate amount of solvent (such as alcohol solvent) and stirred, and then the steps of extraction, concentration and crystallization are carried out.
For the current study, 8-[5-(5, phenyl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one is generally considered safe. However, as a compound, adverse reactions may occur if used in excess or for a long time. Before using 8-[5-(5,-2-methoxyphenyl]-5,7-dihydroxyxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, it is best to consult a doctor's advice, to understand the specific dosage and method of use.
Last Update：2024-04-09 21:01:54
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Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
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Product Name: Bilobetin (Standard) Visit Supplier Webpage Request for quotationCAS: 521-32-4
Tel: 609-228-6898
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