52727-44-3
2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one
CAS: 52727-44-3
Molecular Formula: C10H8N2O2
52727-44-3 - Names and Identifiers
| Name | 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one |
| Synonyms | 2H-oxazolo[2,3-b]quinazolin-5(3H)-one 2,3-Dihydro-oxazolo[2,3-b]quinazolin-5-one 2,3-DIHYDRO-5H-OXAZOLO[2,3-B]QUINAZOLIN-5-ONE 2,3-Dihydro-5H-oxazolo[2,3-b]quinazolin-5-one 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one 5H-Oxazolo[2,3-b]quinazolin-5-one, 2,3-dihydro- 2,3-dihydro-5H-[1,3]oxazolo[2,3-b]quinazolin-5-one |
| CAS | 52727-44-3 |
| InChI | InChI=1/C10H8N2O2/c13-9-7-3-1-2-4-8(7)11-10-12(9)5-6-14-10/h1-4H,5-6H2 |
52727-44-3 - Physico-chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molar Mass | 188.18 |
| Density | 1.47 |
| Melting Point | 160-163°C(lit.) |
| Boling Point | 330°C at 760 mmHg |
| Flash Point | 153.4°C |
| Vapor Presure | 0.000171mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.719 |
52727-44-3 - Risk and Safety
| WGK Germany | 3 |
52727-44-3 - Introduction
2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one(2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one) is an organic compound with the following properties and uses:
Nature:
-Appearance: 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one is a solid, common white or slightly yellow crystals.
-Solubility: It is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane, but its solubility in water is relatively low.
Use:
- 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one has some biological activities, so it can be used as a pharmaceutical intermediate.
-The compound can also be used as a catalyst in organic synthesis.
Preparation Method:
- 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one has a variety of preparation methods, one of which is commonly used to synthesize through a multi-step reaction. One method is by first reacting hydrogen cyanide with an anthranilate ester to form an aminobenzoate derivative. The azaquinazoline derivatives are then formed by diazotization and amine reactions. Finally, the final product, 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one, was obtained by cyclization of ethyl red ketone.
Safety Information:
- 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one There are currently no detailed safety data and toxicological information publicly available. However, as a laboratory compound, it must be used with appropriate safety measures and under the guidance of qualified personnel.
Nature:
-Appearance: 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one is a solid, common white or slightly yellow crystals.
-Solubility: It is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane, but its solubility in water is relatively low.
Use:
- 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one has some biological activities, so it can be used as a pharmaceutical intermediate.
-The compound can also be used as a catalyst in organic synthesis.
Preparation Method:
- 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one has a variety of preparation methods, one of which is commonly used to synthesize through a multi-step reaction. One method is by first reacting hydrogen cyanide with an anthranilate ester to form an aminobenzoate derivative. The azaquinazoline derivatives are then formed by diazotization and amine reactions. Finally, the final product, 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one, was obtained by cyclization of ethyl red ketone.
Safety Information:
- 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one There are currently no detailed safety data and toxicological information publicly available. However, as a laboratory compound, it must be used with appropriate safety measures and under the guidance of qualified personnel.
Last Update：2024-04-09 20:45:29
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Product Name: 2,3-DIHYDRO-5H-OXAZOLO[2,3-B]QUINAZOLIN-5-ONE Visit Supplier Webpage Request for quotationCAS: 52727-44-3
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