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54522-53-1

Methylprotogracillin

CAS: 54522-53-1

Molecular Formula: C52H86O23

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54522-53-1 - Names and Identifiers

Name Methylprotogracillin
Synonyms NSC 698792
Kikubasaponin
Methylprotogracillin
methyl protogracillin
22-O-Methylprotogracillin
b-D-Glucopyranoside, (3b,22a,25R)-26-(b-D-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-a-L-mannopyranosyl-(12)-O-[b-D-glucopyranosyl-(13)]-
β-D-Glucopyranoside, (3β,22α,25R)-26-(β-D-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-
CAS 54522-53-1
EINECS 300-008-5

54522-53-1 - Physico-chemical Properties

Molecular FormulaC52H86O23
Molar Mass1079.24
Density1.46±0.1 g/cm3(Predicted)
Solubility DMSO, Pyridine, Methanol, Ethanol, etc.
AppearancePowder
pKa12.78±0.70(Predicted)
Storage Condition2-8℃

54522-53-1 - Reference Information

overview Dioscorea panicula is the rhizome of Dioscorea panicula DiscoreanipponicaMakino of Dioscorea panicula. It has the effects of dispelling wind and dampness, relaxing tendons and collaterals, promoting blood circulation and relieving pain, relieving cough and relieving asthma. Steroidal saponins are the main active ingredients in Dioscorea. Modern pharmacological studies have found that the total saponins of Dioscorea has anti-rheumatoid arthritis, lowering uric acid, relieving asthma, and anti-tumor activities. They are widely used clinically in rheumatic arthralgia, flutter injury, cough and asthma, and coronary heart disease. "Chinese Pharmacopoeia" 2015 edition of the first Dioscorea under the item only a single component of diosgenin quality control. In recent years, although there have been reports on the quality control of Dioscorein, many studies have been conducted on Dioscorein, Dioscorein, Proto-Dioscorein, Pseudo-Proto-Dioscorein and Methyl Proto-fine Dioscorein in Dioscorein. The study intends to use HPLC method to determine six components of Dioscorea chinensis, Dioscorea chinensis, Dioscorea chinensis, Dioscorea chinensis, Pseudo-Dioscorea chinensis, Dioscorea chinensis and Dioscorea chinensis saponin, and evaluate Dioscorea chinensis from different producing areas, so as to fully reflect the internal quality of Dioscorea chinensis through multi-index component control method and provide basis for the quality control of Dioscorea chinensis.
biological activity Methyl protogracillin (NSC-698793) can be isolated from the root of Dioscorea opposite Thunb and has strong anti-cancer activity.
Last Update:2024-04-10 22:29:15
54522-53-1
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54522-53-1
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