58749-23-8
Licochalcone B
CAS: 58749-23-8
Molecular Formula: C16H14O5
58749-23-8 - Names and Identifiers
| Name | Licochalcone B |
| Synonyms | LICOCHALCONEB Licochalcone B Licoagrochalcone B 3,4,4'-Trihydroxy-2-Methoxychalcone 3,4,4'-Trihydroxy-2-methoxy-trans-chalcone (E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one (2E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one 2-Propen-1-one,3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)- |
| CAS | 58749-23-8 |
| InChI | InChI=1/C16H14O5/c1-21-16-11(5-9-14(19)15(16)20)4-8-13(18)10-2-6-12(17)7-3-10/h2-9,17,19-20H,1H3/b8-4+ |
58749-23-8 - Physico-chemical Properties
| Molecular Formula | C16H14O5 |
| Molar Mass | 286.28 |
| Density | 1.369±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 196-197℃ |
| Boling Point | 550.5±50.0 °C(Predicted) |
| Flash Point | 208.5°C |
| Solubility | Soluble in DMSO, methanol |
| Vapor Presure | 9.95E-13mmHg at 25°C |
| Appearance | Yellow crystalline powder |
| pKa | 7.80±0.15(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.684 |
| Physical and Chemical Properties | Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the root of licorice. |
58749-23-8 - Reference
| Reference Show more | 1. Zhou Yuemei, Feng Chao, Shi Yuhua, et al. Study on HPLC fingerprint of licorice extract and determination of multi-index components [J]. China Modern Applied Pharmacy, 2020, v.37(09):26-31. 2. Cai Shuhui, Zhao huachong, Jia Meng, Zhao Xiaoli, Chi Yumei, Zhang Wen, Wang Honglan, Di Liuqing. Quality Evaluation of roasted licorice based on HPLC fingerprint and multi-component quantitative analysis [J]. Chinese Journal of Traditional Chinese Medicine, 2021,46(01):118-124. 3. [IF = 2.233] Zhihui Huang et al."Licochalcone B induced apoptosis and autophagy in osteosarcoma tumor cells via the inactivation of PI3K/AKT/mTOR pathway." BIOLOGICAL & PHARMACEUTICAL BULLETIN |
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