6-Fluoroindoline
6-Fluoroindoline
CAS: 2343-23-9
Molecular Formula: C8H8FN
6-Fluoroindoline - Names and Identifiers
| Name | 6-Fluoroindoline |
| Synonyms | 6-Fluoroindoline 6-Fluoro-2,3-dihydro-indole 6-FLUORO-2,3-DIHYDRO-1H-INDOLE 6-Fluoro-2,3-dihydro-1H-indole 1H-Indole, 6-fluoro-2,3-dihydro- 6-Fluoroindoline in stock Factory 6-FLUORO-2,3-DIHYDRO-1H-INDOLE HYDROCHLORIDE |
| CAS | 2343-23-9 |
| InChI | InChI=1/C8H8FN/c9-7-2-1-6-3-4-10-8(6)5-7/h1-2,5,10H,3-4H2 |
6-Fluoroindoline - Physico-chemical Properties
| Molecular Formula | C8H8FN |
| Molar Mass | 137.15 |
| Density | 1.154±0.06 g/cm3(Predicted) |
| Boling Point | 70-72 °C(Press: 0.3 Torr) |
| Flash Point | 79.3°C |
| Vapor Presure | 0.224mmHg at 25°C |
| pKa | 4.44±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.538 |
6-Fluoroindoline - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
6-Fluoroindoline - Introduction
6-Fluoroindoline (6-Fluoroindoline) is an organic compound. Its chemical formula is C8H6FN, and the structure is that fluorine replaces a hydrogen atom on the indoline molecule.
Regarding the properties of 6-Fluoroindoline, it is a white to light yellow solid that is not volatile at room temperature and pressure. It has a melting point of about 76-78 degrees Celsius and a boiling point of about 265-270 degrees Celsius. The compound is less soluble in water and more soluble in organic solvents.
6-Fluoroindoline has certain application value in pharmaceutical research, pharmaceutical synthesis and organic synthesis. It is widely used in the synthesis of various biologically active compounds, such as intermediates for drugs. In addition, 6-Fluoroindoline can also be used to synthesize materials with luminescent properties.
The method for preparing 6-Fluoroindoline is usually by introducing a fluorine atom on the indoline compound. A common method is to introduce fluorine atoms by the reaction of a fluorinated sulfoxide (N-fluoropyridinium) or N-fluoropyrrolidine sulfate (tosylate).
Regarding the safety information of 6-Fluoroindoline, since it is an organic compound, the chemical safety operation regulations should be followed during operation. It may cause irritation to the eyes, skin and respiratory tract, so use and handle with appropriate protective measures, such as gloves, goggles and protective masks. At the same time, it should be stored in a dry, well-ventilated place, away from heat sources and open flames. If ingested or inhaled, please seek medical attention.
Regarding the properties of 6-Fluoroindoline, it is a white to light yellow solid that is not volatile at room temperature and pressure. It has a melting point of about 76-78 degrees Celsius and a boiling point of about 265-270 degrees Celsius. The compound is less soluble in water and more soluble in organic solvents.
6-Fluoroindoline has certain application value in pharmaceutical research, pharmaceutical synthesis and organic synthesis. It is widely used in the synthesis of various biologically active compounds, such as intermediates for drugs. In addition, 6-Fluoroindoline can also be used to synthesize materials with luminescent properties.
The method for preparing 6-Fluoroindoline is usually by introducing a fluorine atom on the indoline compound. A common method is to introduce fluorine atoms by the reaction of a fluorinated sulfoxide (N-fluoropyridinium) or N-fluoropyrrolidine sulfate (tosylate).
Regarding the safety information of 6-Fluoroindoline, since it is an organic compound, the chemical safety operation regulations should be followed during operation. It may cause irritation to the eyes, skin and respiratory tract, so use and handle with appropriate protective measures, such as gloves, goggles and protective masks. At the same time, it should be stored in a dry, well-ventilated place, away from heat sources and open flames. If ingested or inhaled, please seek medical attention.
Last Update：2024-04-09 21:54:55
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