6188-43-8
H-imidazo[1,2-a]pyridine-3-carbaldehyde
CAS: 6188-43-8
Molecular Formula: C8H6N2O
6188-43-8 - Names and Identifiers
6188-43-8 - Physico-chemical Properties
| Molecular Formula | C8H6N2O |
| Molar Mass | 146.15 |
| Density | 1.24±0.1 g/cm3(Predicted) |
| Melting Point | 127-129 °C |
| pKa | 4.15±0.50(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.641 |
6188-43-8 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
6188-43-8 - Introduction
H-imidazo[1,2-a]pyridine-3-carbaldehyde is an organic compound with the chemical formula C10H7N2O. It is a light yellow solid with a special aroma.
H-imidazo[1,2-a]pyridine-3-carbaldehyde has a wide range of applications in medicinal chemistry. It is an important intermediate for many pharmaceutical compounds, such as anti-tumor drugs, immunosuppressants and antimicrobial drugs. It can also be used as a precursor for photosensitive dyes, photochromic materials and photochemical sensors.
H-imidazo[1,2-a]pyridine-3-carbaldehyde are prepared by two common methods. One is obtained by the reaction of an isocyanate with imidazo [1,2-a] pyridine. The other is prepared by reacting imidazo [1,2-a] pyridine with formaldehyde.
With regard to safety information, H-imidazo[1,2-a]pyridine-3-carbaldehyde specific toxicity data are limited, appropriate chemical laboratory practices and personal protective measures are required. During handling, direct contact with skin and eyes should be avoided, and appropriate protective gloves and goggles should be worn. At the same time, it should be operated in a well-ventilated place to avoid inhaling harmful gases. If splashing or aspiration occurs, rinse immediately with plenty of water and seek medical attention. In addition, H-imidazo[1,2-a]pyridine-3-carbaldehyde should be stored in a dry, cool, ventilated place, away from fire and organic matter.
H-imidazo[1,2-a]pyridine-3-carbaldehyde has a wide range of applications in medicinal chemistry. It is an important intermediate for many pharmaceutical compounds, such as anti-tumor drugs, immunosuppressants and antimicrobial drugs. It can also be used as a precursor for photosensitive dyes, photochromic materials and photochemical sensors.
H-imidazo[1,2-a]pyridine-3-carbaldehyde are prepared by two common methods. One is obtained by the reaction of an isocyanate with imidazo [1,2-a] pyridine. The other is prepared by reacting imidazo [1,2-a] pyridine with formaldehyde.
With regard to safety information, H-imidazo[1,2-a]pyridine-3-carbaldehyde specific toxicity data are limited, appropriate chemical laboratory practices and personal protective measures are required. During handling, direct contact with skin and eyes should be avoided, and appropriate protective gloves and goggles should be worn. At the same time, it should be operated in a well-ventilated place to avoid inhaling harmful gases. If splashing or aspiration occurs, rinse immediately with plenty of water and seek medical attention. In addition, H-imidazo[1,2-a]pyridine-3-carbaldehyde should be stored in a dry, cool, ventilated place, away from fire and organic matter.
Last Update：2024-04-09 21:11:58
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